Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Catalyst‐Free Preparation of Perfluoroalkyl‐Phosphoryl Substituted Furans from 1‐Perfluoroalkyl 1,3‐Diketones in Two Steps
View through CrossRef
AbstractA two‐step catalyst‐free procedure for the construction of 3‐perfluoroalkyl‐2‐(phosphoryl)methyl furans from commercially available 1‐perfluoroalkyl 1,3‐diketones is reported. Propargylic alcohols, prepared by direct alkynylation of the diketones, react with PCl3 via [2,3]‐sigmatropic rearrangement – enolate cyclization sequence, leading to multifunctional furans. The reaction mechanism is supported by DFT study. In addition, the bioactivity modifying effect of phosphoryl group on 3‐perfluoroalkyl furans is depicted.magnified image
Title: Catalyst‐Free Preparation of Perfluoroalkyl‐Phosphoryl Substituted Furans from 1‐Perfluoroalkyl 1,3‐Diketones in Two Steps
Description:
AbstractA two‐step catalyst‐free procedure for the construction of 3‐perfluoroalkyl‐2‐(phosphoryl)methyl furans from commercially available 1‐perfluoroalkyl 1,3‐diketones is reported.
Propargylic alcohols, prepared by direct alkynylation of the diketones, react with PCl3 via [2,3]‐sigmatropic rearrangement – enolate cyclization sequence, leading to multifunctional furans.
The reaction mechanism is supported by DFT study.
In addition, the bioactivity modifying effect of phosphoryl group on 3‐perfluoroalkyl furans is depicted.
magnified image.
Related Results
Biodiesel Production from Canola Oil Using TiO2CaO as a Heterogenous Catalyst
Biodiesel Production from Canola Oil Using TiO2CaO as a Heterogenous Catalyst
Biodiesel is one of the renewable energy sources that is an alternative to fossil diesel that is non-toxic and produces less CO emissions. Transesterification process is a conventi...
Catalytic Pyrolysis of LDPE Plastic Wastes over Mortar Cement Catalyst
Catalytic Pyrolysis of LDPE Plastic Wastes over Mortar Cement Catalyst
A CaO based catalyst synthesized from mortar previously used in construction was chosen for pyrolysis of LDPE plastic waste. The samples were calcined at temperatures of 500 and 80...
Characterization of Equilibrium Catalysts from the Fluid Catalytic Cracking Process of Atmospheric Residue
Characterization of Equilibrium Catalysts from the Fluid Catalytic Cracking Process of Atmospheric Residue
In the FCC conversion of heavy petroleum fractions as atmospheric residues, the main challenge for refiners to achieve the quantity and quality of various commercial products depen...
Prediction of catalyst bed density and simulation of glycerol steam reformer for hydrogen production
Prediction of catalyst bed density and simulation of glycerol steam reformer for hydrogen production
A simple method was proposed to generate a rigid model and to predict the packing density of catalyst using Blender software. It is a free and open-source 3D creation suite animati...
Ni Catalyst on Zsm-22 Nanofibers Bundles with Good Catalytic Performance in the Hydroisomerization of N-Dodecane
Ni Catalyst on Zsm-22 Nanofibers Bundles with Good Catalytic Performance in the Hydroisomerization of N-Dodecane
Developing non-noble catalyst with high performance is significant in the hydroisomerization of long-chain n-alkane to iso-alkanes. Herein, ZSM-22 with nanofiber bundles morphology...
Characterization of Equilibrium Catalysts from the Fluid Catalytic Cracking Process of Atmospheric Residue
Characterization of Equilibrium Catalysts from the Fluid Catalytic Cracking Process of Atmospheric Residue
In the FCC conversion of heavy petroleum fractions as atmospheric residues, the main challenge for refiners to achieve the quantity and quality of various commercial products depen...
Conversion of Furans by Baeyer-Villiger Monooxygenases
Conversion of Furans by Baeyer-Villiger Monooxygenases
Various furans are considered as valuable platform chemicals as they can be derived from plant biomass. Yet, for their exploitation, follow-up chemistry is required. Here we demons...
Photochemistry of α-diketones. II. Some photo-oxidation reactions
Photochemistry of α-diketones. II. Some photo-oxidation reactions
The photochemical behaviour of 1,1,4,4-tetramethyl-2,3-dioxotetralin (I) in the presence of oxygen has been thoroughly investigated in the solvents methanol and benzene. Products w...