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Uso de mTOR en el Trasplante Renal

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En los pacientes con enfermedad renal crónica en estadio avanzado el trasplante renal es la principal medida terapéutica a implementar, sin embargo, el sistema inmune debe ser modulado para prevenir el riesgo de la perdida del injerto renal. El tratamiento inmunosupresor debe ser individualizado según el riesgo inmunológico de cada paciente; los mTOR son una alternativa que se debe considerar en los pacientes que serán sometidos a un trasplante renal, existen diferentes protocolos de uso, estas modalidades de inicio de fármaco pueden ser  desde la conversión de Novo, la conversión temprana y la tardía; cada uno aporta ventajas y desventajas al paciente trasplantado. El medicamento no está excepto a efectos secundarios a con considerar dentro de los mas destacados la dislipidemia, el retardo en la cicatrización de heridas, la Neumo iris, la proteína Roa y el riesgo de rechazo agudo humoral.
Title: Uso de mTOR en el Trasplante Renal
Description:
En los pacientes con enfermedad renal crónica en estadio avanzado el trasplante renal es la principal medida terapéutica a implementar, sin embargo, el sistema inmune debe ser modulado para prevenir el riesgo de la perdida del injerto renal.
El tratamiento inmunosupresor debe ser individualizado según el riesgo inmunológico de cada paciente; los mTOR son una alternativa que se debe considerar en los pacientes que serán sometidos a un trasplante renal, existen diferentes protocolos de uso, estas modalidades de inicio de fármaco pueden ser  desde la conversión de Novo, la conversión temprana y la tardía; cada uno aporta ventajas y desventajas al paciente trasplantado.
El medicamento no está excepto a efectos secundarios a con considerar dentro de los mas destacados la dislipidemia, el retardo en la cicatrización de heridas, la Neumo iris, la proteína Roa y el riesgo de rechazo agudo humoral.

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