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Xeroderma pigmentosum with bilateral ocular surface squamous neoplasia and review of the literature
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Xeroderma pigmentosum is a rare genetic disorder associated with various ocular malignancies. Here we report a single paediatric case of xeroderma pigmentosum with bilateral ocular surface squamous neoplasia (OSSN) presenting with diffuse lesion in one eye and a large mass in the other eye. Diffuse OSSN in one eye was treated with topical chemotherapy using mitomycin-C (0.04%) and the large OSSN in the other eye was treated with a combination of surgery and topical chemotherapy. Long-term follow-up and a multimodality treatment approach are necessary to identify and manage recurrences of OSSN in XP.
Title: Xeroderma pigmentosum with bilateral ocular surface squamous neoplasia and review of the literature
Description:
Xeroderma pigmentosum is a rare genetic disorder associated with various ocular malignancies.
Here we report a single paediatric case of xeroderma pigmentosum with bilateral ocular surface squamous neoplasia (OSSN) presenting with diffuse lesion in one eye and a large mass in the other eye.
Diffuse OSSN in one eye was treated with topical chemotherapy using mitomycin-C (0.
04%) and the large OSSN in the other eye was treated with a combination of surgery and topical chemotherapy.
Long-term follow-up and a multimodality treatment approach are necessary to identify and manage recurrences of OSSN in XP.
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