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SELVa: Simulator of Evolution with Landscape Variation
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Organisms evolve to increase their fitness, a process that may be described as climbing the fitness landscape. However, the fitness landscape of an individual site, i.e., the vector of fitness values corresponding to different variants at this site, can change with time due to changes in the environment or substitutions at other epistatically interacting sites. We present SELVa, the Simulator of Evolution with Landscape Variation, aimed at modeling the substitution process under a changing single position fitness landscape in a set of evolving lineages forming a phylogeny of arbitrary shape. Written in Java and distributed as an executable jar file, SELVa provides a flexible framework that allows the user to choose from a number of implemented rules governing landscape change.
Availability
https://github.com/bazykinlab/SELVa
Title: SELVa: Simulator of Evolution with Landscape Variation
Description:
Organisms evolve to increase their fitness, a process that may be described as climbing the fitness landscape.
However, the fitness landscape of an individual site, i.
e.
, the vector of fitness values corresponding to different variants at this site, can change with time due to changes in the environment or substitutions at other epistatically interacting sites.
We present SELVa, the Simulator of Evolution with Landscape Variation, aimed at modeling the substitution process under a changing single position fitness landscape in a set of evolving lineages forming a phylogeny of arbitrary shape.
Written in Java and distributed as an executable jar file, SELVa provides a flexible framework that allows the user to choose from a number of implemented rules governing landscape change.
Availability
https://github.
com/bazykinlab/SELVa.
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SELVa: Simulator of evolution with landscape variation
SELVa: Simulator of evolution with landscape variation
Organisms evolve to increase their fitness, a process that may be described as climbing the fitness landscape. However, the fitness landscape of an individual site, i.e., the vecto...