Search engine for discovering works of Art, research articles, and books related to Art and Culture
ShareThis
Javascript must be enabled to continue!

Gastrointestinal Tract Duplications, a Multicenter study

View through CrossRef
Background: Gastrointestinal tract duplications are uncommon congenital abnormalities with variable clinical presentations, ranging from abdominal distension to intestinal obstruction. Objective: To describe the clinical characteristics, surgical management, and outcomes of pediatric patients with gastrointestinal tract duplications at a tertiary center. Methods: This retrospective study was conducted on 28 pediatric patients diagnosed with gastrointestinal tract duplications. Inclusion criteria comprised patients who underwent surgical management with complete medical records. Data on demographics, clinical presentation, anatomical site, duplication type, associated anomalies, surgical procedures, and postoperative outcomes were analyzed. Clinical evaluation, imaging, and histopathology confirmed diagnoses. Surgical approaches included resection with primary anastomosis, stoma formation, excision/enucleation, and partial excision with mucosal stripping, depending on lesion type and location. Results: The most prevalent symptoms were abdominal distension and vomiting (50%), followed by abdominal mass (28.6%). Ileal duplications were most frequent (67.8%), followed by jejunal (14.3%) and gastric (7.1%) lesions. Cystic duplications predominated (60.7%). Resection with primary anastomosis was performed in 75% of patients. Overall, 23 patients (82.1%) had favorable outcomes, while 5 (17.9%) experienced complications, primarily sepsis (4 cases) and anastomotic leak (1 case). Conclusion: Gastrointestinal tract duplications mainly present in early childhood with a slight male predominance. Early diagnosis and appropriate surgical management, primarily resection with anastomosis, result in favorable outcomes, with complications largely related to infection.
Title: Gastrointestinal Tract Duplications, a Multicenter study
Description:
Background: Gastrointestinal tract duplications are uncommon congenital abnormalities with variable clinical presentations, ranging from abdominal distension to intestinal obstruction.
Objective: To describe the clinical characteristics, surgical management, and outcomes of pediatric patients with gastrointestinal tract duplications at a tertiary center.
Methods: This retrospective study was conducted on 28 pediatric patients diagnosed with gastrointestinal tract duplications.
Inclusion criteria comprised patients who underwent surgical management with complete medical records.
Data on demographics, clinical presentation, anatomical site, duplication type, associated anomalies, surgical procedures, and postoperative outcomes were analyzed.
Clinical evaluation, imaging, and histopathology confirmed diagnoses.
Surgical approaches included resection with primary anastomosis, stoma formation, excision/enucleation, and partial excision with mucosal stripping, depending on lesion type and location.
Results: The most prevalent symptoms were abdominal distension and vomiting (50%), followed by abdominal mass (28.
6%).
Ileal duplications were most frequent (67.
8%), followed by jejunal (14.
3%) and gastric (7.
1%) lesions.
Cystic duplications predominated (60.
7%).
Resection with primary anastomosis was performed in 75% of patients.
Overall, 23 patients (82.
1%) had favorable outcomes, while 5 (17.
9%) experienced complications, primarily sepsis (4 cases) and anastomotic leak (1 case).
Conclusion: Gastrointestinal tract duplications mainly present in early childhood with a slight male predominance.
Early diagnosis and appropriate surgical management, primarily resection with anastomosis, result in favorable outcomes, with complications largely related to infection.

Related Results

Resolving the insertion sites of polymorphic duplications reveals a HERC2 haplotype under selection
Resolving the insertion sites of polymorphic duplications reveals a HERC2 haplotype under selection
ABSTRACT Polymorphic duplications in humans have been shown to contribute to phenotypic diversity. However, the evolutionary forces that maintain...
Duplications and retrogenes are numerous and widespread in modern canine genomic assemblies
Duplications and retrogenes are numerous and widespread in modern canine genomic assemblies
Abstract Recent years have seen a dramatic increase in the number of canine genome assemblies available. Duplications are an important source of evolutionary novelt...
Multiple Concurrent Pilonidal Sinuses: Case report and Literature review
Multiple Concurrent Pilonidal Sinuses: Case report and Literature review
Abstract Introduction: Concurrent pilonidal sinuses (PNSs) at distinct locations are extremely rare. This report highlights an exceptional case of a young female presenting with th...
Gejala Gastrointestinal pada Pasien COVID-19
Gejala Gastrointestinal pada Pasien COVID-19
Abstract: Patients suffering from corona virus desease of 2019 (COVID-19) could have gastro-intestinal symptoms such as diarrhea, vomiting, and stomach pain. Studies show that huma...
Phosphodiesterase-5 Inhibitors for Lower Urinary Tract Symptoms in Men
Phosphodiesterase-5 Inhibitors for Lower Urinary Tract Symptoms in Men
Objective: To review the efficacy of phosphodiesterase-5 (PDE-5) inhibitors for the treatment of lower urinary tract symptoms in men. ...
Myc super-enhancer dynamics in T-ALL
Myc super-enhancer dynamics in T-ALL
Abstract Mutations in non-coding regulatory elements are increasingly recognized as critical drivers of cancer developme...
Spanish Breast Cancer Research Group (GEICAM)
Spanish Breast Cancer Research Group (GEICAM)
This section provides current contact details and a summary of recent or ongoing clinical trials being coordinated by Spanish Breast Cancer Research Group (GEICAM). Clinical trials...

Back to Top