Shereshevsky — Turner Syndrome: Cardiometabolic Manifestations

Aim. To demonstrate, using a clinical case, the impact of a large number of cardiometabolic risk factors on the development of cardiovascular diseases in Shereshevsky — Turner syndrome. Key points. The prevalence of cardiovascular diseases and cardiovascular mortality in adult women with Shereshevsky — Turner syndrome is significantly higher than in the general population. In the presented clinical case, a patient with mosaic Shereshevsky — Turner syndrome, despite long-term hormone replacement therapy, developed a silent myocardial infarction, to which such cardiometabolic risk factors as smoking, arterial hypertension, hypothyroidism, and poor control of type 1 diabetes mellitus contributed. The specific features of the myocardial infarction course in this patient also include a discrepancy between the area of myocardial damage according to echocardiography and the diameter of the infarct-related coronary artery. Conclusion. Women with Shereshevsky — Turner syndrome require continuous, multifactorial lifelong monitoring for the prevention, early detection, and treatment of cardiovascular diseases. Keywords: Shereshevsky — Turner syndrome, acute myocardial infarction, cardiometabolic factors