Investigating the resurgence of malaria prevalence in South Africa between 2015 and 2018: A scoping review

Abstract Background Malaria remains a serious concern in most African countries, causing nearly one million deaths globally every year. The review aims to examine the extent and nature of the resurgence of malaria prevalence in South Africa.Method Using the Arksey and O'Malley framework, this scoping review included articles published between the year 2015 and 2018 on the resurgence of malaria prevalence in South Africa. Articles were searched from October 2018 to January 2019 using these electronic databases: CINAHL, Pubmed, Science Direct and SCOPUS. Grey literature from Google Scholar was also hand searched. Key search terms and subject headings such as climate variables; climate changes; climatic factors; malaria resurgence; malaria reoccurrence, and malaria increase over epidemic regions in South Africa were used to identify relevant articles. Articles for selection and characterization were performed by three independent reviewers. Data collected were synthesized qualitatively.Results A total number of 748 studies were identified. Among these, 24 studies met the inclusion criteria. The results were grouped by factors (four main themes) that influenced the malaria resurgence: Climatic, Epidemiological, Socio-economic, and Environmental factors. Climatic factors were found to be the major factor responsible for the resurgence of malaria, as more than 55% of the selected articles were climate focused. This was followed by epidemiological, socio-economic and environmental factors, in that order. Grey literature from Google Scholar yielded no results.Conclusion This study shows that malaria transmission in South Africa is more associated with climate. Climate-based malaria models could be used as early warning systems of malaria over the epidemic regions in South Africa. Since epidemiological factors also play significant roles in the transmission, regular and unrelaxed use of indoor residual spraying (IRS) should be encouraged in these regions. While some studies have indicated that vectors have developed resistance to insecticides, continuous research on developing new insecticides that could alter the resistance are ongoing. Individuals should also be educated on the importance and the usefulness of these deliveries. Furthermore, all efforts to eradicate malaria in South Africa must also target the epidemic neighbouring countries.