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Predictors of polytrauma outcome in children on the first day of treatment in ICU

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The objective was to identify predictors of polytrauma outcome in children on the first day of treatment in ICU.Materials and methods. Design – multicenter, cohort, retrospective, observational study. 225 children with polytrauma were examined. The average age of children was 10 (4–14) years. There were 148 (65.8%) boys. In 65.2% of cases, the injury was received as a result of a traffic accident, catatrauma occurred in 32.6% of polytrauma. The AIS score was 34 (25–48) and the PTS score was 5 (2.0–8.0). The duration of artificial lung ventilation was 12 (0–97) hours, and treatment in ICU – 5 (2–8) days. Death was in 14.2% of cases. Results. An increase in Glasgow Coma Scale (GCS) and SpO2 by one unit (1 point, 1%) was found to reduce the risk of adverse outcome by 44% and 9%, respectively, and an increase in creatinine concentration and international normalized ratio by one unit increased the probability of patient death by 4.3 and 15.8 times, respectively. A mathematical formula was developed to assess the risk of an unfavorable outcome of polytrauma in children at the time of admission to the ICU: OR = exp (3.74–0.58 · [GCS score] – 0.09 · [SpO2] + 0.06 · [Creatinine] + 2.62 · [INR]. Its accuracy is 96.4%; sensitivity 83.4%; specificity 98.7%.Conclusion. Predictors of unfavorable outcome of polytrauma in children at admission to ICU are low scores on the Glasgow Coma Scale, severe hypoxemia, coagulopathy and kidney damage.
Title: Predictors of polytrauma outcome in children on the first day of treatment in ICU
Description:
The objective was to identify predictors of polytrauma outcome in children on the first day of treatment in ICU.
Materials and methods.
Design – multicenter, cohort, retrospective, observational study.
225 children with polytrauma were examined.
The average age of children was 10 (4–14) years.
There were 148 (65.
8%) boys.
In 65.
2% of cases, the injury was received as a result of a traffic accident, catatrauma occurred in 32.
6% of polytrauma.
The AIS score was 34 (25–48) and the PTS score was 5 (2.
0–8.
0).
The duration of artificial lung ventilation was 12 (0–97) hours, and treatment in ICU – 5 (2–8) days.
Death was in 14.
2% of cases.
 Results.
An increase in Glasgow Coma Scale (GCS) and SpO2 by one unit (1 point, 1%) was found to reduce the risk of adverse outcome by 44% and 9%, respectively, and an increase in creatinine concentration and international normalized ratio by one unit increased the probability of patient death by 4.
3 and 15.
8 times, respectively.
A mathematical formula was developed to assess the risk of an unfavorable outcome of polytrauma in children at the time of admission to the ICU: OR = exp (3.
74–0.
58 · [GCS score] – 0.
09 · [SpO2] + 0.
06 · [Creatinine] + 2.
62 · [INR].
Its accuracy is 96.
4%; sensitivity 83.
4%; specificity 98.
7%.
Conclusion.
Predictors of unfavorable outcome of polytrauma in children at admission to ICU are low scores on the Glasgow Coma Scale, severe hypoxemia, coagulopathy and kidney damage.

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