21 cases of laparoscopic central pancreatectomy

Abstract Objective: To investigate the experience of laparoscopic central pancreatectomy. Methods: The perioperative data of 21 patients who underwent laparoscopiccentral pancreatectomy were retrospectively analyzed from September 2017 to November 2022 in Ningbo Medical Center Lihuili Hospital (Xingning Branch and Eastern Branch). According to these data, we summarized the treatment experience of laparoscopic central pancreatectomy. Results: All the operations were successfully completed without intraoperative conversion to open surgery. In these operations, intraoperative blood transfusion was in 1 case, intraoperative cholangiography was performed in 2 cases, and intraoperative fluoroscopic laparoscopic assistance was performed in 4 cases. The operative time ranged from 140-560 min (average 221.5min), and the estimated intraoperative bleeding volume ranged from 50-800 ml (average 180.9 ml). Postoperative pathology confirmed that 5 cases were intraductal papillary mucinous neoplasm, 6 cases were serous cystic neoplasms, 3 cases were mucinous cystic neoplasms, 3 cases weresolid pseudopapillary neoplasms, 3 cases were neuroendocrine tumors and 1 case was pancreatic ductal adenocarcinoma. The maximum tumor diameter ranged from 1.0-8.5 cm (average 2.9 cm).There was no one case of postoperative common bile duct stenosis and biliaryleakage. Among them, there were 4 cases of biochemical leakage, 15 cases of grade B pancreatic fistula, and 2 cases of grade C pancreatic fistula. Conclusion: As a procedure for preserving pancreatic function, laparoscopic central pancreatectomy had certain surgical risks and a high probability of postoperative pancreatic fistula whichshould be performed by experienced surgeons. Ethical approval number: KY2022SL213-01