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Evolving Trends in the Management of Acute Appendicitis During COVID‐19 Waves: The ACIE Appy II Study
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Abstract
Background
In 2020, ACIE Appy study showed that COVID‐19 pandemic heavily affected the management of patients with acute appendicitis (AA) worldwide, with an increased rate of non‐operative management (NOM) strategies and a trend toward open surgery due to concern of virus transmission by laparoscopy and controversial recommendations on this issue. The aim of this study was to survey again the same group of surgeons to assess if any difference in management attitudes of AA had occurred in the later stages of the outbreak.
Methods
From August 15 to September 30, 2021, an online questionnaire was sent to all 709 participants of the ACIE Appy study. The questionnaire included questions on personal protective equipment (PPE), local policies and screening for SARS‐CoV‐2 infection, NOM, surgical approach and disease presentations in 2021. The results were compared with the results from the previous study.
Results
A total of 476 answers were collected (response rate 67.1%). Screening policies were significatively improved with most patients screened regardless of symptoms (89.5% vs. 37.4%) with PCR and antigenic test as the preferred test (74.1% vs. 26.3%). More patients tested positive before surgery and commercial systems were the preferred ones to filter smoke plumes during laparoscopy. Laparoscopic appendicectomy was the first option in the treatment of AA, with a declined use of NOM.
Conclusion
Management of AA has improved in the last waves of pandemic. Increased evidence regarding SARS‐COV‐2 infection along with a timely healthcare systems response has been translated into tailored attitudes and a better care for patients with AA worldwide.
Wiley
Francesco Pata
Marcello Di Martino
Mauro Podda
Salomone Di Saverio
Benedetto Ielpo
Gianluca Pellino
Abba Julio
Abdullah Alshamrani
Abdullah Alturkistani
Abdulrahman Alghamdi
Abdulrahman Almalki
Adam Orengia
Adnan Kuvvetli
Adolfo Pisanu
Adrian Smith
Adriana Michelle Treviño Figueroa
Aeris Jane Nacion
Ahmad Alhazmi
Ahmad Bouhuwaish
Ahmad Khalid
Ahmed Alsufyani
Ainhoa Valle Rubio
Akshay Bavikatte
Akshay Kumar
Al‐Radjid Jamiri
Alberto de San Ildefonso Pereira
Alberto Porcu
Alberto Sartori
Aldo Rocca
Aleksandar Sretenovic
Alessandro Anselmo
Alessandro De Luca
Alexandros Charalabopoulos
Alexios Tzivanakis
Alfonso Bandin
Alfonso Nájar
Alice Frontali
Alsulaimani Faisal
Amaia Martínez Roldan
Amal Hamid
Ana André
Ana Minaya‐Bravo
Andre Das
Andrea Bondurri
Andrea Costanzi
Andrea Lucchi
Andrei Mihailescu
Andrea Police
Andres Mendoza Zuchini
Angela Romano
Angelo Iossa
Antonella Chessa
Antonella Tromba
Antonio Castaldi
Antonio Brillantino
Antonio Ferronetti
Antonio Giuliani
Antonio Ramos‐De la Medina
Antonio Tarasconi
Arcangelo Picciariello
Argyrios Ioannidis
Ari Leppäniemi
Arshad Rashid
Ashrarur Rahman Mitul
Asif Mehraj
Asim laharwal
Atif Iqbal
Athanasios Liarakos
Athanasios Marinis
Beatriz de Andrés‐Asenjo
Belén Matías‐García
Belinda De Simone
Ben Creavin
Ben Stubbs
Brian Goh
Branislav Jovanovic
Bruno Sensi
Carlo Gazia
Carlos Cerdán
Carlos Javier Gómez Díaz
Carlos Petrola Chacón
Carlos Yánez
Carmelo Lo Faro
Caroline Reinke
Casandra Dominguez
Charudutt Paranjape
Charlotte Thomas
Chia Chi Fung
Chiara De Lucia
Chiu Hiu Fung Jennifer
Christian Ovalle‐Chao
Claudio Guerci
Cleo Kenington
Corina Gica
Cristina Folliero
Cristopher Varela
Daniel Popowich
Daniele Delogu
Daniele Zigiotto
Danilo Vinci
Dario D'Antonio
David Alessio Merlini
David Merlini
David Moro‐Valdezate
Deborah Keller
Diana Cristiana Nicolaescu
Diego Sasia
Edgar Rodas
Dimitrios Linardoutsos
Domenico Russello
Pedro Alfonso Nájar‐Castañeda
Habil Gregor Stavrou
Edoardo Rosso
Edoardo Saladino
Edoardo Ricciardi
Eduardo Smith‐Singares
Efstratia Baili
Eleftheria Douka
Eleonora Guaitoli
Elisa Francone
Elisa Maria Vaterlini
Elisa Sefora Pierobon
Emilio Morales
Emilio Peña Ros
Enrico Benzoni
Enrico Erdas
Enrico Pinotti
Enrique Colás‐Ruiz
Ernesto Laterza
Esteban Foianini
Eugenia Cardamone
Eugenio Licardie
Fabio Marino
Fahad Alsofyani
Fahad Qahtani
Farhan Khan
Fatlum Maraska
Fatmir Saliu
Fausto Madrid
Fausto Rosa
Federico Luvisetto
Felipe Alconchel
Felipe Pareja‐Ciuro
Fernanda Neves
Ferdinando Agresta
Fernando Cordera
Fernando Pardo
Fernando Mendoza‐Moreno
Fernando Munoz‐Flores
Francesca Maria Silvestri
Francesca Paola Tropeano
Francesca Pecchini
Francesca Serio
Francesco Colombo
Francesco Di Marzo
Francesco Ferrara
Francesco Lancellotti
Francesco Litta
Francesco Martini
Francesco Roscio
Francisco Blanco‐Antona
Francisco Javier Quezada Barcenas
Francisco Schlottmann
Gabriel Herrera‐Almario
Gabrielle van Ramshorst
Gaetano Gallo
Gaetano Luglio
Georgios Kampouroglou
Georgios Papadopoulos
Gerardo Arredondo
Giacomo Calini
Giampaolo Formisano
Giampaolo Galiffa
Gian Marco Palini
Gianluca Colucci
Gianluca Pagano
Gianluca Vanni
Gianmaria Casoni Pattacini
Gianpiero Gravante
Giorgio Lisi
Giovanni Bellanova
Giovanni De Nobili
Giovanni Sammy Necchi
Giovanni Sinibaldi
Giulia Bacchiocchi
Giulia Bagaglini
Giulia Maggi
Giuliano Izzo
Giulio Argenio
Giuseppe Brisinda
Giuseppe Esposito
Giuseppe Frazzetta
Giuseppe Massimiliano De Luca
Giuseppe Nigri
Giuseppe Sica
Gonzalo Martin‐Martin
Gustavo Armand Ugon
Gustavo Martinez‐Mier
Gustavo Miguel Machain Vega
Gustavo Nari
Herald Nikaj
Ignacio Neri
Igor Alberdi San Roman
Iliya Fidoshev
Iñaki Martínez
Ionut Negoi
Irene Ortega
Irune Vicente Rodríguez
Isabel Cornejo
Ismael Mora‐Guzmán
Issam al‐Najami
Ivan Romic
Izaskun Balciscueta
James Olivier
Jan Lammel‐Lindemann
Jana Dziakova
Javier Salinas
Jelena Pejanovic Jovanovic
Jeryl Anne Silvia Reyes
Joanne Salas
Jose Antonio Diaz‐Elizondo
Jose Gustavo Parreira
Juan Bellido
Juan Salamea
Juan Carlos Martín del Olmo
Juliana María Ordoñez
Sofi Junaid
Justin Davies
Kapil Sahnan
Kebebe Bekele
Kelvin Voon
Leandro Siragusa
Lorenzo Petagna
Luca Ferrario
Luca Giordano
Luca Nespoli
Luca Pio
Lucia Moletta
Luciano Curella
Lucio Taglietti
Luigi Bonavina
Luigi Conti
Luis Eduardo Pérez‐Sánchez
Luis Felipe Cabrera Vargas
Luis Sánchez‐Guillén
Luis Tallon‐Aguilar
Mansoor Khan
Marcello Giuseppe Spampinato
Marcelo Viola
Marcelo Viola Malet
Marco Angrisani
Marco Calussi
Marco Catarci
Marco Giordano
Marco Materazzo
Marco Milone
Marco Pellicciaro
Marco Vito Marino
María Daniela Moreno Villamizar
Maria Giulia Lolli
Maria Irene Bellini
Maria Lemma
Maria Michela Chiarello
Mario Montes‐Manrique
Mario Rodriguez‐Lopez
Mario Serradilla‐Martín
Mark Peter
Marta Paniagua‐García‐Señoráns
Martin Rutegård
Martin Salö
Massimiliano Silveri
Massimiliano Veroux
Matteo Nardi
Matteo Rottoli
Matti Tolonen
Mauricio Pedraza Ciro
Mauricio Zuluaga
Maurizio Iacobone
Mauro Montuori
Mazin Ali
Melody García Domínguez
Menna Maria Paola
Micaela Piccoli
Michela Campanelli
Michele De Rosa
Michele Manigrasso
Michele Maruccia
Michele Torre
Michele Zuolo
Miguel Pera
Mihiri Weerasekera
Mikel Prieto
Min Myat Thway
Mohamed Shaat
Mohammad Azfar
Mostafa Shalaby
Muhammad Asif Raza
Muhammad Umar Younis
Muhammed Elhadi
Mujahid Ali
Musab AlThomali
Nadiah Al Amri
Nagendra Dudi‐Venkata
Nahar Alselaim
Neil Smart
Nelson Trelles
Nicolò Falco
Niccolo Petrucciani
Nicola Antonacci
Nicola Cillara
Nicolae Gica
Nicolò Pecorelli
Nicolò Tamini
Nikolaos Machairas
Nura Feituri
Nuria Ortega Torrecilla
Octavio Avila Mercado
Ohood AlAamer
Oktay Irkorucu
Omar Alsherif
Oreste Claudio Buonomo
Orestes Valles‐Guerra
Orestis Ioannidis
Oscar Isaac Hernández Palmas
Oscar Sanz Guadarrama
Osman Bozbiyik
Pablo Rodrigues
Pamela Milito
Paolo Panaccio
Panagiotis Dorovinis
Paola Prieto
Paolo Baroffio
Patrizia Marsanic
Pawel Ajawin
Peng Soon Koh
Pietro Anoldo
Piotr Major
Qasem Alharthi
Rashid Lui
Riccardo Caruso
Richard Brady
Rishi Rattan
Rishi Singhal
Roberta Angelico
Roberta Maria Isernia
Roberta Tutino
Roberto Peltrini
Rodrigo Tejos
Roosevelt Fajardo
Rossella Elia
Salvador Morales‐Conde
Sami Benli
Sara Fuentes
Sara Gortázar de las Casas
Sara Ortiz de Guzmán Aragón
Sara Vertaldi
Selmy Awad
Sergio Gentilli
Sergio Alberto Weckmann Lujan
Serkan Tayar
Shabab Althobaiti
Silvia Di Giovanni
Soliman Ghedan
Sonia Pérez‐Bertólez
Sonja Chiappetta
Spiros Delis
Stefano Scaringi
Süleyman Çetinkünar
Stylianos Kykalos
Syed Muhammad Ali
Sylvia Krivan
Tak Lit Derek Fung
Tarik Delko
Tatiana Nicolás López
Tercio De Campos
Teresa Calderón Duque
Teresa Perra
Theodore Liakakos
Theodoros Daskalakis
Tijmen Koëter
Tiku Zalla
Tomás Elosua González
Tommaso Campagnaro
Toure Alpha Oumar
Ugo Grossi
Valentina Sosa
Valentina Testa
Valentina Tomajer
Valeria Andriola
Valeria Tonini
Valerio Celentano
Valerio Voglino
Venkateswara Rao Katta
Víctor Hugo García Orozco
Victor Turrado‐Rodriguez
Victor Visag‐Castillo
Victoria Graham
Viktor Rachkov
Vincenzo Papagni
Vincenzo Vigorita
Virginia Jiménez Carneros
Vittoria Bellato
Wolf Bechstein
Yuksel Altinel
Zutoia Balciscueta
Title: Evolving Trends in the Management of Acute Appendicitis During COVID‐19 Waves: The ACIE Appy II Study
Description:
Abstract
Background
In 2020, ACIE Appy study showed that COVID‐19 pandemic heavily affected the management of patients with acute appendicitis (AA) worldwide, with an increased rate of non‐operative management (NOM) strategies and a trend toward open surgery due to concern of virus transmission by laparoscopy and controversial recommendations on this issue.
The aim of this study was to survey again the same group of surgeons to assess if any difference in management attitudes of AA had occurred in the later stages of the outbreak.
Methods
From August 15 to September 30, 2021, an online questionnaire was sent to all 709 participants of the ACIE Appy study.
The questionnaire included questions on personal protective equipment (PPE), local policies and screening for SARS‐CoV‐2 infection, NOM, surgical approach and disease presentations in 2021.
The results were compared with the results from the previous study.
Results
A total of 476 answers were collected (response rate 67.
1%).
Screening policies were significatively improved with most patients screened regardless of symptoms (89.
5% vs.
37.
4%) with PCR and antigenic test as the preferred test (74.
1% vs.
26.
3%).
More patients tested positive before surgery and commercial systems were the preferred ones to filter smoke plumes during laparoscopy.
Laparoscopic appendicectomy was the first option in the treatment of AA, with a declined use of NOM.
Conclusion
Management of AA has improved in the last waves of pandemic.
Increased evidence regarding SARS‐COV‐2 infection along with a timely healthcare systems response has been translated into tailored attitudes and a better care for patients with AA worldwide.
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