Sclerosing angiomatoid nodular transformation (SANT) of spleen mimicking a splenic abscess

ABSTRACT Introduction: SANT of the spleen is a benign lesion that does not recur after splenectomy with unknown etiology. Presentation of the case: We report a case of sclerosing angiomatoid nodular transformation (SANT) of the spleen mimicking a splenic abscess in a patient with imaging studies that failed to differentiate this lesion from other splenic lesions. Discussion: SANT of the spleen is a rare condition, with only less than 100 cases reported in the literature. Clinically, SANT is only a kind of described pathological diagnostic conception. As in our case, these splenic lesions are often incidental findings on imaging studies performed for other reasons. Conclusion: The patient was treated with splenectomy, which has proved to be both diagnostic and therapeutic. Although histology can lead to the diagnosis of vascular tumor, immunohistochemistry is the only way to confirm the diagnosis. Highlights