Javascript must be enabled to continue!

Recent Developments in the Synthesis of Pyrido[1,2-a]benzimidazoles

Pyrido[1,2-a]benzimidazole is one of the most important azaheterocyclic compounds consisting of three fused aromatic rings. Molecules containing this core have displayed a wide range of applications in the field of medicinal chemistry. The synthesis of pyrido[1,2-a]benzimidazole and its derivatives has attracted organic chemists because of its tremendous utility in interdisciplinary branches of chemistry. In this context, this review discusses the main advances in the synthesis of pyrido[1,2-a]benzimidazoles via metal-mediated and metal-free reactions from 2000 to 2016.1 Introduction2 Synthetic Approaches to Pyrido[1,2-a]benzimidazoles2.1 Type I: Transition-Metal-Catalyzed Methods2.2 Type II: Metal-Free Approaches3 Conclusion

Georg Thieme Verlag KG

Kamal Kapoor Parthasarathi Das Rajni Khajuria Sk. Rasheed Chhavi Khajuria

Synthesis

2018

Title: Recent Developments in the Synthesis of Pyrido[1,2-a]benzimidazoles

Description:

Pyrido[1,2-a]benzimidazole is one of the most important azaheterocyclic compounds consisting of three fused aromatic rings.

Molecules containing this core have displayed a wide range of applications in the field of medicinal chemistry.

The synthesis of pyrido[1,2-a]benzimidazole and its derivatives has attracted organic chemists because of its tremendous utility in interdisciplinary branches of chemistry.

In this context, this review discusses the main advances in the synthesis of pyrido[1,2-a]benzimidazoles via metal-mediated and metal-free reactions from 2000 to 2016.

1 Introduction2 Synthetic Approaches to Pyrido[1,2-a]benzimidazoles2.

1 Type I: Transition-Metal-Catalyzed Methods2.

2 Type II: Metal-Free Approaches3 Conclusion.

Back

There are four types of pyridopyrimidines namely pyrido[2,3-d], pyrido[3,4-d], pyrido[ 4,3-d]pyrimidines, and pyrido[3,2-d]pyrimidines. Different methods of preparation of pyrido[2...

STABILIZATION OF POLYETHYLENE AND OTHER POLYOLEFINS BY PHENOTHIAZINE DERIVATIVES

This paper presents the results of the synthesis and study of the thermostabilizing properties of a number of new derivatives, as well as previously known derivatives of Phenothiaz...

Towards novel antimicrobials

The widespread use of antimicrobials has led to the development of resistance to most known active compounds. This has led to the necessity to discover new drugs or adopt new strat...

Benzimidazoles Pharmacodynamics in Equine Strongyles

Our research aimed to assess the effectiveness of four benzimidazoles: albendazole, fenbendazole, mebendazole and thiabendazole against equine strongyles. The tests were performed ...

Synthesis, Characterization and Antibacterial Activity of Some Novel Pyrido[2,3-b]indole, Morpholine and Chalcone Hybrid Compounds

In present investigation, a novel series of (E)-3-(2-morpholino-9H-pyrido[2,3-b]indol-3-yl)-1-phenylprop-2-en-1-one and its derivatives (5a-f) were synthesized by condensation reac...

Green Synthesis of Potential Benz Imidazole Scaffolds: Comprehensive Review

Benzimidazoles and their derivatives, such as antiulcer, analgesic, and anthelmintic medications, are incredibly important medicinal agents. An important field of study in organic ...

Emerging Multidrug Anthelmintic Resistance in Sheep Gastro-Intestinal Nematodes in Sweden

Gastrointestinal nematodes are clinically and economically important parasites of small ruminants worldwide which are frequently controlled with anthelmintics. The efficacies of be...

α,α-Dibromoketones as Synthetic Equivalents of α-Bromoketones for the Synthesis of Thiazolo[3,2-a]benzimidazoles

Abstract: Utilization of α,α-dihalocarbonyl compounds as synthetic equivalents to α-halocarbonyl compounds has been explored in the synthesis of a wide range of highly useful heter...

Email:
Password:

Email:

Recent Developments in the Synthesis of Pyrido[1,2-a]benzimidazoles

Related Results