Efficacy and Mechanism of Fuyang Yiyin Method in Pulmonary Fibrosis Based on the Theory of Yang Transforming into Qi, Yin Constituting Form

Idiopathic pulmonary fibrosis (IPF) is a common pathological manifestation of various pulmonary diseases, characterized by insidious onset and progression to irreversible organ failure. Currently, there are still inadequacies in the diagnosis and treatment of IPF. Traditional Chinese medicine (TCM) can intervene in IPF at multiple levels, targets, and pathways, possessing significant advantages in the treatment of IPF. The underlying mechanisms deserve further exploration. The theory of Yang Transforming into Qi, Yin Constituting Form in Huangdi Neijing embodies the specific meanings of yin and yang, containing profound views on life and disease. The pathological changes of IPF conform to the theory of yin and yang in Yang Transforming into Qi, Yin Constituting Form, where deficiency of yang transforming into qi and excessive formation of yin constitute the core pathogenesis of IPF. This paper proposes the principle of Fuyang Yiyin for IPF, aiming to nourish the source of fire and dispel yin turbidity, in order to broaden the clinical treatment strategies for IPF.