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Clofazimine in Dermatitis ulcerosa (Pyoderma gangrenosum)

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Five patients suffering from dermatitis ulcerosa (a variant of pyoderma gangrenosum) were treated with clofazimine in a daily dosage of 200 mg orally. Complete healing was noted in 2 patients, partial response in 2, no effect in 1. Side effects were mild and transitory in form of a red coloring of the skin (all patients) and mild ichthyosis (2 patients).
Title: Clofazimine in Dermatitis ulcerosa (Pyoderma gangrenosum)
Description:
Five patients suffering from dermatitis ulcerosa (a variant of pyoderma gangrenosum) were treated with clofazimine in a daily dosage of 200 mg orally.
Complete healing was noted in 2 patients, partial response in 2, no effect in 1.
Side effects were mild and transitory in form of a red coloring of the skin (all patients) and mild ichthyosis (2 patients).

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