Frequency of Subclinical Hypothyroidism among Patients of Polycysitic Ovarian Syndrome (PCOS)

Introduction: Polycystic ovarian disorder is the most frequent kind of persistent anovulation caused by androgen extra, affecting 6-12% of fertile women. PCOS is seen as a complex condition through a variable origin. It has also been linked to greater in metabolic and cardiovascular risk factors. The purpose of our research was to determine the frequency of subclinical hypothyroidism among patients of polycystic ovarian disease presenting in the outpatient department of tertiary care hospital Methods: The Study was a cross-sectional study which was conducted in Gynecology & Obstetrics Department, Lady Aitchison Hospital, Lahore. All polycystic ovarian disease patients were enrolled. Participants' blood samples were drawn utilizing aseptic methods and transported to a pathology laboratory for serum TSH levels to be measured. Subclinical hypothyroidism was found to be common in polycystic ovarian individuals diagnosed. SPSS v24 was used to enter and evaluate data. The Chi-square method was conducted to test the relevance of post-stratification. A p-value of 0.06 was believed important. Results: Total 136 cases with polycystic ovarian disease were selected for this study. Mean age was 28.4±7.9 years. Among 136 patients, 26(19.1%) had subclinical hypothyroidism. By stratification of subclinical hypothyroidism, it was found that age >30 years and obese had extensive effect having subclinical hypothyroidism (p=0.00001, p=0.002). Conclusion: Subclinical hypothyroidism may be a modifiable risk factor, associated with polycystic ovarian disease. Steps should be taken to minimize more this risk factor by screening and early intervention. Keywords: Subclinical Hypothyroidism, Polycystic Ovarian Disease.