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DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHOD FOR THE QUANTITATIVE DETERMINATION OF LANSOPRAZOLE AND RABEPRAZOLE
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The article is devoted to the development and validation of methods for spectrophotometric quantitative determination of lansoprazole and rabeprazole in the substance and various prepara-tions. 96% ethyl alcohol was chosen as a common solvent. The working wavelengths for lanso-prazole were set at 285 nm, and for rabeprazole at 275 nm. The relative error of determination is ± 0.32% for “Lansil” capsules, ± 0.58% for “Rabeloc” lyophilized powder. The validation of methods for spectrophotometric quantitative determination of lansoprazole and rabeprazole in standard samples for some parameters was carried out.
Uptodate In Medicine LLC
Title: DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHOD FOR THE QUANTITATIVE DETERMINATION OF LANSOPRAZOLE AND RABEPRAZOLE
Description:
The article is devoted to the development and validation of methods for spectrophotometric quantitative determination of lansoprazole and rabeprazole in the substance and various prepara-tions.
96% ethyl alcohol was chosen as a common solvent.
The working wavelengths for lanso-prazole were set at 285 nm, and for rabeprazole at 275 nm.
The relative error of determination is ± 0.
32% for “Lansil” capsules, ± 0.
58% for “Rabeloc” lyophilized powder.
The validation of methods for spectrophotometric quantitative determination of lansoprazole and rabeprazole in standard samples for some parameters was carried out.
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