GW24-e0606 Dyslipidemia in Xinjiang Uygur Autonomous Region, China

Objectives The aim of this study was to estimate the status of dyslipidemia awareness, treatment, and control in Xinjiang, China. Methods A multiple-ethnic, community-based, cross-sectional study of cardiovascular risk factors (the Cardiovascular Risk Survey [CRS]) was conducted in Xinjiang (northwestern China) between October 2007 and March 2010. We used a stratified sampling method to select a representative sample of the general population, including Chinese Hans, Uygurs, and Kazaks, in this geographic area. Seven cities (Urumqi, Kelamayi, Hetian, Zhaosu, Fukang, Tulufan, and Fuhai) were chosen and, based on the government records of registered residences, one participant was randomly selected from each household. The eligibility criterion for the study was > 35 years of age. Results A total of 14,618 participants (5,757 Hans, 4,767 Uygurs, and 4,094 Kazakhs), were randomly selected from 26 villages in 7 cities and were invited to participate. Participants with incomplete data were excluded; thus, 13, 609 participants (5,326 Hans, 4,448 Uygurs, and 3,835 Kazaks), 35-74 years of age, were analysed. We found that 7,187 participants had dyslipidemia. Among the participants with dyslipidemia, only 45.90% were aware of their serum lipid levels, 21.98% were taking lipid-lowering medication, and 17.00% achieved target serum lipid concentrations. In Han, 53.84% were aware of their serum lipid levels, 19.42% were taking lipid-lowering medication, and 16.92% achieved target serum lipid concentrations. In Uygur, 42.05% were aware of their serum lipid levels, 27.54% were taking lipid-lowering medications, and 16.23% achieved target serum lipid concentrations. In Kazak, 37.24% were aware of their serum lipid levels, 19.91% were taking lipid-lowering medications, and 18.01% achieved target serum lipid concentrations. Conclusions Dyslipidemia is highly prevalent in Xinjiang. The proportion of participants with dyslipidemia who were aware, treated, and controlled is unacceptably low. These results underscore the urgent need to develop national strategies to improve the prevention, detection, and treatment of dyslipidemia in Xinjiang (northwestern China).