Systematic Review on the Efficacy of Icon Resin Infiltration on White Spot Lesions

Background: Resin infiltration is a new therapeutic technique for WSLs (white spot lesions) that may bridgenonoperative and operative treatment options. It’s a minimally invasive procedure for filling, reinforcing,and stabilizing demineralized enamel without drilling or compromising good tooth structure. It has alsobeen found to slow the progression of caries in lesions that are too advanced to be treated with fluoride. Thecurrent investigation of this systematic review is to evaluate the efficacy of ICON® resin infiltration on WSLs.This literature review was conducted and reported according to the PRISMA (Preferred Reporting Items forSystematic Review and Metaanalysis) statement. Seven databases (PubMed, Cochrane Library, CINAHL, OVIDMEDLINE, EMBASE, Grey Literature, Wiley Online Library) were used. The MeSH terms used were ‘Icon resininfiltration, ‘ white spot lesions, and ‘clinical trials. PICOS analysis of Population- Participants with white spotlesions; Intervention- Icon Resin Infiltration; Comparison- Comparing with other different therapies; Outcome-Regression or disappearance of lesions; Study design- Randomized controlled trials. Five cross-sectional studieswere included in this systematic review for the quality assessment of the efficacy of Icon resin infiltration onwhite spot lesions. All five studies reported a statistically significant difference between the Icon resin infiltration,lesion loss ratio, and color change. This systematic review concludes that the Icon resin infiltration on white spotlesion is effective during the initial period, i.e. first three months. Over time there is a color change in its masking.However, it is effective in reducing the lesion loss ratio.