Flavonoid C-glucosides and monosaccharides from Combretum indicum

Introduction: Combretum indicum belongs to Combretaceae. This species was known to possess diverse bioactivities and chemical constituents. This paper reported the isolation and structural elucidation of five compounds from leaves of Combretum indicum collected in Ho Chi Minh City. Method: From the dried powder of Combretum indicum, the crude extract was obtained by maceration method in methanol at room temperature. Then this extract was separated into different extracts by absorbed on silica gel and eluted with different solvents. The organic compounds were then isolated by chromatography methods and were identified by MS and NMR spectra interpretation. Results: Five compounds comprising vitexin (1), orientin (2), isoorientin (3), D-glucose (4), and D-fructose (5) were isolated. Conclusion: To the best of our knowledge, all isolated compounds were reported from this species for the first time.