Analgesic and Antipyretic Activity Study of Aqueous Stem Extract of Sarcostemma acidum Voigt

Sarcostemma acidum Voigt is a leafless plant of the family Apocynaceae. Plant is locally known as Somlata. It is a traditional medicinal plant used to prepare Somras. The plant is mainly found in Bihar, West Bengal, Odisha and South India. It is mostly grown in dry rocky places. S. acidum is a shrub, more branched but no leaves. The plant extract of S. acidum contains carbohydrates, glycosides, alkaloids, tannins, flavonoids, proteins, free amino acids, steroids, triterpenoids, fixed oil, fats, mucilage, gums and waxes. Based on its ethnomedicinal uses the different parts of S. acidum was used in disease condition like otitis media, dog bite, snake bite, rabies, emesis and leprosy.The juice of this plant was used as natural restorative for health. S. acidum stem extract inhibits spermatogenesis and reduce the sperm count. Also the extract of S.acidum shown antipsychotic effect. This study was taken to determine the other therapeutic properties of S. acidum, like analgesic andantipyretic activity by using the aqueous extract of the stem of this plant. So, here the evaluation of analgesic activity study was taken by using hot plate method, antipyretic activity study was taken brewer’s yeast induced pyrexia rat model. The results were shown that the aqueous extract of S.acidum has significant analgesic andantipyretic effect.