Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Antifungal activity of Terminalia chebula fruit extracts
View through CrossRef
The present study was aimed to investigate the anticandidal and antifungal potential of dried fruit extracts of Terminalia chebula against Candida albicans, C. tropicalis C. glabrata, C. krusei, C. parapsilosis, and Aspergillus flavus, A. niger, A. fumigatus, Trichophyton mentagrophytes, T. rubrum, Microsporum gypseum. Phytochemical analysis of methanol extracts of T. chebula dried fruits showed the presence of flavonoids, alkaloids, glycosides, saponins, tannins, terpenoids and steroids. Among the tested four extracts, the methanol extracts of T. chebula dried fruits exhibited the highest antifungal activity and their inhibition zone was ranged between 7.5 to 19.5mm. MIC and MFC values were between 62.5-250μg/ml and 250-500μg/ml respectively. Zone of inhibition (19.5 mm), MIC (62.5µg/ml) and MFC (125µg/ml) values observed in methanolic extracts of T. chebula dried fruits against A. fumigates and T. mentagrophytes. Our findings proved that methanolic extracts of T. chebula dried fruits were possessed substantial anticandidal and antifungal properties.
Title: Antifungal activity of Terminalia chebula fruit extracts
Description:
The present study was aimed to investigate the anticandidal and antifungal potential of dried fruit extracts of Terminalia chebula against Candida albicans, C.
tropicalis C.
glabrata, C.
krusei, C.
parapsilosis, and Aspergillus flavus, A.
niger, A.
fumigatus, Trichophyton mentagrophytes, T.
rubrum, Microsporum gypseum.
Phytochemical analysis of methanol extracts of T.
chebula dried fruits showed the presence of flavonoids, alkaloids, glycosides, saponins, tannins, terpenoids and steroids.
Among the tested four extracts, the methanol extracts of T.
chebula dried fruits exhibited the highest antifungal activity and their inhibition zone was ranged between 7.
5 to 19.
5mm.
MIC and MFC values were between 62.
5-250μg/ml and 250-500μg/ml respectively.
Zone of inhibition (19.
5 mm), MIC (62.
5µg/ml) and MFC (125µg/ml) values observed in methanolic extracts of T.
chebula dried fruits against A.
fumigates and T.
mentagrophytes.
Our findings proved that methanolic extracts of T.
chebula dried fruits were possessed substantial anticandidal and antifungal properties.
Related Results
Phytochemical study and pharmacological activity of Terminalia chebula fruit extracts activity as Dihydrofolate Reductase enzyme inhibitors associated with antioxidant effect: In vitro study
Phytochemical study and pharmacological activity of Terminalia chebula fruit extracts activity as Dihydrofolate Reductase enzyme inhibitors associated with antioxidant effect: In vitro study
Dihydrofolate reductase (DHFR) is a fundamental enzyme in producing the precursor of purines and pyrimidines for biosynthesis of DNA, RNA and amino acids at various stages. It is c...
Multimodal neuroprotection by Terminalia chebula fruit extract against haloperidol-induced neurotoxicity in rats
Multimodal neuroprotection by Terminalia chebula fruit extract against haloperidol-induced neurotoxicity in rats
Terminalia chebula is a plant with a long history of use in traditional medicine for its medicinal properties. In this study, we investigated the potential neuroprotective effects ...
British Food Journal Volume 35 Issue 5 1933
British Food Journal Volume 35 Issue 5 1933
The Fruit Control Act, 1924, is an important one as it provides for the establishment of a Fruit Control Board, and is described as an “Act to make Provision for Control of the Fru...
Evaluation of Antimicrobial Activity of Extracts of Terminalia chebula and Piper nigrum against Streptococcus mutans: An In Vitro Study
Evaluation of Antimicrobial Activity of Extracts of Terminalia chebula and Piper nigrum against Streptococcus mutans: An In Vitro Study
Objective: Dental caries is an infectious disease in which S. mutans plays a key role. Haphazard and irrational use of antibiotics leads to antibiotic resistance and fatal diarrhoe...
Terminalia chebula Mediated Silver Nanoparticles and Its Antibacterial Activity against Oral Pathogens
Terminalia chebula Mediated Silver Nanoparticles and Its Antibacterial Activity against Oral Pathogens
Background: Dental infections cause chronic disorders such as gingivitis, periodontitis, and dental caries when left untreated, resulting in irreversible tooth loss. However, solid...
A Review on Bael Fruit Showing Antifungal Activity Against Candida Albicans and Aspergillus Niger
A Review on Bael Fruit Showing Antifungal Activity Against Candida Albicans and Aspergillus Niger
The Bael fruit (Aegle Marmelos), a widely recognized medicinal plant in traditional medicine, has gainedattention for its antifungal properties. This review highlights its potentia...
Bioactive components of the methanolic extracts of Terminalia spp. against fungal pathogens in Drosophila melanogaster (Diptericin-lacZ II) as a Model
Bioactive components of the methanolic extracts of Terminalia spp. against fungal pathogens in Drosophila melanogaster (Diptericin-lacZ II) as a Model
Fungal pathogens are becoming prospective agents of bioterrorism; there is widespread emergence of fungi such as Aspergillus species being implicated in invasive diseases, leading ...
A Classical Review on Different Varieties of Fruit - Terminalia Chebula (Haritaki)
A Classical Review on Different Varieties of Fruit - Terminalia Chebula (Haritaki)
Terminalia chebula is a member of the Combretaceae family. Known as the "king of medicines," Harad is among the oldest medicinal plants. Various medical systems, including Ayurveda...