A Comparative Clinical Study to Evaluate the Efficacy of Topical Application of Panchavalkala Cream Versus Povidone Iodine Ointment in the Management of Postoperative Wound of Parikartika (Chronic Fissure-In-Ano)

Parikartika, a significant Guda-Gata Vikara in Ayurveda, is marked by severe Kartanavat and Chhedanavat Shoola in the Guda Pradesha. Hence, in the present study application of Panchavalkala cream in Group A and povidone iodine ointment in Group B were used to evaluate their efficacy in the management of Parikartika w.s.r. to chronic fissure in ano. Aims and Objectives: 1. To explore and understand the clinical features, etiology, and management approaches of Parikartika and fissure-in-ano. 2. To evaluate the therapeutic effect of Panchavalkala cream in the treatment of post-operative wound in cases of Parikartika (chronic fissure-in-ano). 3. To assess the efficacy of povidone iodine ointment in the management of post-operative wound of Parikartika (chronic fissure-in-ano). 4. To compare the effectiveness of topical Panchavalkala cream versus povidone iodine ointment in healing post-operative wound in Parikartika. Methods: This study is a randomized comparative clinical trial. A total of 60 patients diagnosed with Parikartika and meeting the inclusion criteria were selected, regardless of their sex, religion, occupation, or economic status. These patients were then randomly allocated into two groups, each consisting of 30 participants. viz Group A & Group B. Intervention: Group A: Patients underwent fissurectomy followed by the topical application of Panchavalkala cream twice daily for 21 days. Group B: Patients underwent fissurectomy followed by the topical application of povidone iodine ointment twice daily for 21 days. Conclusion: The study concludes that in the management of Parikartika, fissurectomy followed by the application of either Panchavalkala cream and povidone iodine ointment is effective and plays a significant role in healing Parikartika Vyadhi.