A case report on primigravida with myasthenia gravis: outcome of pregnancy

Primigravida refers to a woman who is pregnant for the first time.  It is a unique experience for the woman. Usually, any minor alignment during this time will lead to anxiety. The prevalence rate of myasthenia gravis in pregnancy is 1 in 20,000. The main reason behind the cause of the disease is improper secretion of acetylcholine, huge secretion of cholinesterase, and non-responsive muscle fibers. The purpose of this case study is to introduce the outcome of pregnancy with myasthenia gravis. This case was taken at X private hospital. A 27-year-old primigravida woman with 38 weeks of pregnancy was the first known case of myasthenia gravis. She was diagnosed with myasthenia gravis thymic hyperplasia in November 2020. The patient is then managed with a surgical procedure, i.e., thymectomy, on 18 September 2021. The patient was receiving distinon (pyridostigmine) 60 mg. It requires the intraoperative collaboration of the neurology and obstetrics departments in managing myasthenia gravis during pregnancy. A successful elective caesarean section was done on the patient's request under spinal anaesthesia on 13 April 2023. The male newborn, with a birth weight of 2.825 gm was delivered. The newborn was transferred to the NICU for further surveillance and did not show any sign of muscular weakness. The baby was healthy at the time of discharge.