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Myelofibrosis and Systemic Lupus erythematosus: Reversal of Fibrosis with High-Dose Corticosteroid Therapy
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A case of myelofibrosis in association with systemic lupus erythematosus (SLE) is reported. Acute thrombocytopenia and a bleeding tendency developed in a 24-year-old woman with SLE. Bone marrow aspiration was unsuccessful due to myelofibrosis. Pulse therapy with methylprednisolone reversed both thrombocytopenia and myelofibrosis. A review of the literature revealed that the coexistence of SLE and myelofibrosis is a rare occurrence. Only 7 cases, to our knowledge, have ever been reported in detail. The present case is the 3rd in which myelofibrosis was reversed by corticosteroids.
Title: Myelofibrosis and Systemic Lupus erythematosus: Reversal of Fibrosis with High-Dose Corticosteroid Therapy
Description:
A case of myelofibrosis in association with systemic lupus erythematosus (SLE) is reported.
Acute thrombocytopenia and a bleeding tendency developed in a 24-year-old woman with SLE.
Bone marrow aspiration was unsuccessful due to myelofibrosis.
Pulse therapy with methylprednisolone reversed both thrombocytopenia and myelofibrosis.
A review of the literature revealed that the coexistence of SLE and myelofibrosis is a rare occurrence.
Only 7 cases, to our knowledge, have ever been reported in detail.
The present case is the 3rd in which myelofibrosis was reversed by corticosteroids.
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