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ANTIHEMORRHOIDAL ACTIVITY OF DIALIUM GUINEENSE (ICHEREKU) AND THE HAEMATOLOGICAL PROFILES OF GRAVINDEX SUBJECTS IN EMENE ENUGU STATE
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The antihemorrhoidal activity of Dialium guineense (Ichereku) and the haematological profiles of gravindex subjects in Emene Enugu State was investigated in pregnant women suffering from haemorrhoid.
Results showed Dialium guineense has no significant effect in decreasing or increasing the haemoglobin concentrations, packed cell volume, white blood cell count and platelet count (P>0.05) in gravindex subjects, however the extract does have effect in reducing the length and size of the protruded hemorrhoid (P<0.05) in pregnant women after administration of the pulp for ten (10) days.
This reduction in the size of the hemorrhoid which was 2.0cm±0.4 in the subjects before the intake of the pulp and 0.6cm±0.1 could be attributed to the high concentration of flavenoids, Tannins and saponins in the pulp of D. guineense. Flavenoid is a typical plant based compounds which have been shown to possess anti-inflammatory properties which may help reduce swelling and pain associated with hemorrhoids.
Title: ANTIHEMORRHOIDAL ACTIVITY OF DIALIUM GUINEENSE (ICHEREKU) AND THE HAEMATOLOGICAL PROFILES OF GRAVINDEX SUBJECTS IN EMENE ENUGU STATE
Description:
The antihemorrhoidal activity of Dialium guineense (Ichereku) and the haematological profiles of gravindex subjects in Emene Enugu State was investigated in pregnant women suffering from haemorrhoid.
Results showed Dialium guineense has no significant effect in decreasing or increasing the haemoglobin concentrations, packed cell volume, white blood cell count and platelet count (P>0.
05) in gravindex subjects, however the extract does have effect in reducing the length and size of the protruded hemorrhoid (P<0.
05) in pregnant women after administration of the pulp for ten (10) days.
This reduction in the size of the hemorrhoid which was 2.
0cm±0.
4 in the subjects before the intake of the pulp and 0.
6cm±0.
1 could be attributed to the high concentration of flavenoids, Tannins and saponins in the pulp of D.
guineense.
Flavenoid is a typical plant based compounds which have been shown to possess anti-inflammatory properties which may help reduce swelling and pain associated with hemorrhoids.
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