New Isoflavone Glucosides from White Lupin (Lupinus albus L.)

Abstract Further investigation of polar constituents in white lupin roots revealed the presence of genistein 7-O-β-glucoside (1 a), genistein 4′-O-β-glucoside (1 b), 2′-hydroxygenistein 7-O-β-glucoside (2 a) and 2′-hydroxygenistein 4′-O-β-glucoside (2 b) as simple isoflavone gluco­ sides; luteone 7-O-β-glucoside (3 a), licoisoflavone A 7-O-β-glucoside (4 a) and licoisoflavone A 4′-O-β-glucoside (4 b) as prenylated (= 3,3-dimethylallyl-substituted) isoflavone glucosides; and genistein 7-O-β-(6′-O-malonyl)glucoside (1 am) and 2′-hydroxygenistein 7-O-β-(6″-O-malonyl)glueoside (2 am) as malonylated isoflavone glucosides. Six compounds (2 a, 2 b, 3 a, 4 a, 4 b, and 2 am) are new naturally occurring isoflavone glucosides.