Determination of the protective effect of shark cartilage and shark liver oil (SLO) on colon cancer by using experimental DMH

Objectives: It is a known fact that cancer is one of the biggest health problems. There are many different alternative products that are preferred for use among cancer patients. Our study is based on shark cartilage and liver oil as alternative products within alternative treatment (CAM) due to low incidence of cancer in sharks. Method: With this study; it was aimed to search the toxic effects of DMH on colon, SC and SLO ‘s conservative effects against these toxic and carcinogic effects. 40 rats have been classified as follows: 40 DMH group: 4; control group – 6; given DMH but not cured group – 15; given DMH and cured with SC group – 15; given DMH and cured with SLO group. Results and Conclusion: The negative effects of DMH on biochemical, genetic, and pathological were observed in rat column; The treatment of SLO and SC against to colon cancer is thought to be associated with damage and regression of tumor cells. When we look at the numerical results, it can be said that SC is more successful and effective in correcting the effect of DMH. It can be said that our experimental model provides the desired aim and success in this direction.