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A study on the response of FRET based DNA aptasensors in intracellular environment
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AbstractThis paper presents a study of the response of FRET based DNA aptasensors in the intracellular environment. Herein, we extend previous studies of aptasensors functioning in the extracellular environment to detection of antigens in the intracellular environment. An essential step in this research is the use of a novel means of achieving the endocytosis of aptasensors. Specifically, it is demonstrated that functioning aptasensors are successfully endocytosed by functionalizing the aptasensors with endocytosis—inducing DSS peptides.
Springer Science and Business Media LLC
Title: A study on the response of FRET based DNA aptasensors in intracellular environment
Description:
AbstractThis paper presents a study of the response of FRET based DNA aptasensors in the intracellular environment.
Herein, we extend previous studies of aptasensors functioning in the extracellular environment to detection of antigens in the intracellular environment.
An essential step in this research is the use of a novel means of achieving the endocytosis of aptasensors.
Specifically, it is demonstrated that functioning aptasensors are successfully endocytosed by functionalizing the aptasensors with endocytosis—inducing DSS peptides.
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