A Comprehensive Review on Phytochemical and Pharmacological Properties of Alstonia scholaris

In traditional therapeutic systems, Alstonia scholaris is commonly employed. It is used to cure "diarrhoea, malaria, asthma, fever, epilepsy, skin disorders, snake bites", and other conditions in India, Thailand, China, Malaysia, the Philippines, Africa, Australia, and other places because of its abundant natural active components. This review highlights the phytochemical richness and pharmacological potential of Alstonia scholaris (“Saptaparni”), covering its traditional uses, bioactive constituents, and therapeutic activities including analgesic, anti-inflammatory, antibacterial, and anticancer effects. Despite promising in-vitro and in-vivo findings, limited clinical trials and mechanistic data remain major gaps. Further research is essential to validate safety, isolate active compounds, and advance its therapeutic applications.