Anti-Aging Effect of Phyllanthus Emblica (Amla) and Zingiber Officinale (Ginger) on Saccharomyces Cerevisiae

Aging is an age-related disease, and amla and ginger are best known for their anti-bacterial and anti-fungal activity. They also serve as anti-aging activity. Ginger's active ingredients, such as 6-gingerol and 6-shogaol, have anticancer properties against gastrointestinal cancer. Strong antioxidants such as ginger may reduce or even stop the production of free radicals. Amla is rich in vitamin C, contains phenolic compounds, is its main chemical constituent, and has strong antioxidant properties. Other active ingredients found in amla include ellagic acid, gallic acid, 1-O-galloyl-D glucose, chebulininc acid, quercetin, chebulagic acid, kaempferol, mucic acid, 1,4-lactone 3-Ogallate, isocorilagin, chebulanin, mallotusinin, acylated apignin glucoside, and others. Moreover, it possesses anti-oxidative and anti-inflammatory qualities, that help slow down aging. Astragalus membranaceous which slows the ageing process was experimented on in S. cerevisiae, and the results were positive. Therefore, we have taken S.cerevisiae as a model organism to check the anti-aging effect. Various tests were conducted to assess the aging process. Amla outperformed ginger in the chronological lifespan experiment. Aqueous amla showed better result than aqueous ginger in the replicative longevity experiment. In the oxidative assay, amla 100 μl and ginger 50 μl concentration gave the best results. In verifying the antioxidative assay, the highest numbers of dead cells were present in Amla 50 μl, Ginger 50 μl, and Astragalus 75 μl. According to the ANOVA test, the p-value in all the concentrations, i.e., 25 μl, 50 μl, 75 μl, and 100 μl was lesser than 0.05. In Effect of glucose, amla is better than ginger. ThusAmla and Ginger have anti-oxidative and anti-aging properties and are best to be used used daily life.