Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Guinea pig copeptin
View through CrossRef
The vasopressin precursor is composed of 3 domains in line, namely vasopressin, MSEL‐neurophysin and a glycopeptide referred to as copeptin, which are separated during the processing. In guinea pig neurohypophysis, the precursor is partially processed so that a two‐domain fragment, MSEL‐neurophysin ‐ copeptin, can be found along with free MSEL‐neurophysin and copeptin. Guinea pig copeptin has been sequenced. It is a glycopeptide composed of 38 amino acid residues rather than the 39 found in other mammalian copeptins. Compared with other copeptins, that from guinea pig shows a few substitutions and the deletion of one acidic residue, probably in position 32. This deletion might be responsible for incomplete cleavage by the trypsin‐like processing enzyme.
Title: Guinea pig copeptin
Description:
The vasopressin precursor is composed of 3 domains in line, namely vasopressin, MSEL‐neurophysin and a glycopeptide referred to as copeptin, which are separated during the processing.
In guinea pig neurohypophysis, the precursor is partially processed so that a two‐domain fragment, MSEL‐neurophysin ‐ copeptin, can be found along with free MSEL‐neurophysin and copeptin.
Guinea pig copeptin has been sequenced.
It is a glycopeptide composed of 38 amino acid residues rather than the 39 found in other mammalian copeptins.
Compared with other copeptins, that from guinea pig shows a few substitutions and the deletion of one acidic residue, probably in position 32.
This deletion might be responsible for incomplete cleavage by the trypsin‐like processing enzyme.
Related Results
Clinical study of copeptin in serum patiants of heart diseases
Clinical study of copeptin in serum patiants of heart diseases
The study included the estimation copeptin level in serum of healthy and patients with heart diseases . The Results indicated that the level of copeptin in serum was (36.2±1....
Assessment of copeptin and obestatin levels in coronary artery disease patients
Assessment of copeptin and obestatin levels in coronary artery disease patients
Abstract
Background
Acute coronary syndrome (ACS) is classified into acute myocardial infarction (AMI), and unstable angina (UA). They are curren...
DIAGNOSIS VALUE OF SERUM COPEPTIN IN PATIENTS WITH ACUTE MYOCARRDIAL INFARCTION
DIAGNOSIS VALUE OF SERUM COPEPTIN IN PATIENTS WITH ACUTE MYOCARRDIAL INFARCTION
Objective: To investigate the effectiveness of serum copeptin in the diagnosis of acute myocardial infarction.
Patients: A total of 156 cases were enrolled in the study. All were ...
PROCEEDINGS OF THE AUSTRALASIAN SOCIETY OF CLINICAL AND EXPERIMENTAL PHARMACOLOGISTS
PROCEEDINGS OF THE AUSTRALASIAN SOCIETY OF CLINICAL AND EXPERIMENTAL PHARMACOLOGISTS
14th Annual Meeting, December 1980, Canberra1. Effect of dexamethasone on pineal β‐adrenoceptors. C. A. Maxwell, A. Foldes, N. T. Hinks and R. M. Hoskinson2. A clinicopathological ...
PROCEEDINGS OF THE AUSTRALASIAN SOCIETY OF CLINICAL AND EXPERIMENTAL PHARMACOLOGISTS
PROCEEDINGS OF THE AUSTRALASIAN SOCIETY OF CLINICAL AND EXPERIMENTAL PHARMACOLOGISTS
1.Effect of chronic haloperidol treatment on D‐2 receptors labelled by (3H)‐spiperone in homogenates of rat corpus striatum. A. L. Gundlach, D. J. de Vries and P. M. Beart2.The eff...
Copeptin and Nesfatin-1 are interesting interrelated biomarkers playing a role in the pathogenesis of insulin resistance in Chinese obese children
Copeptin and Nesfatin-1 are interesting interrelated biomarkers playing a role in the pathogenesis of insulin resistance in Chinese obese children
Abstract
Background Recently, copeptin and nesfatin-1 have been identified as interesting novel peptides playing a role in the pathogenesis of obesity-related insulin resis...
Novel biomarkers in cardiovascular disease and dysglycaemia
Novel biomarkers in cardiovascular disease and dysglycaemia
<p dir="ltr"><b>Background</b><b>.</b> Cardiovascular disease (CVD) and dysglycaemia are closely interconnected. Dysglycaemia, defined as impaired glu...
Novel biomarkers in cardiovascular disease and dysglycaemia
Novel biomarkers in cardiovascular disease and dysglycaemia
<p dir="ltr"><b>Background</b><b>.</b> Cardiovascular disease (CVD) and dysglycaemia are closely interconnected. Dysglycaemia, defined as impaired glu...