Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Lamotrigine Induced Severe Cutaneous Reaction
View through CrossRef
Antiepileptic drugs are used commonly by physicians, neurologist and neurosurgeons in Nepal. Lamotrigine is an effective antiepileptic drug used as an add-on and monotherapy for a variety of seizure types in both adults and children. Rashes due to AED including SJS and hypersensitivity syndrome leading to hospitalization occur in approximately 0.33% of adults and 0.8% in children. Reactions due to LTG alone occur in around 5.7% of cases. We report probably the first case of this reaction in a 12-year old girl with a brief discussion on its etiology and management. J Nepal Paediatr Soc 2012;32(2):172-174 doi: http://dx.doi.org/10.3126/jnps.v32i2.5608
Title: Lamotrigine Induced Severe Cutaneous Reaction
Description:
Antiepileptic drugs are used commonly by physicians, neurologist and neurosurgeons in Nepal.
Lamotrigine is an effective antiepileptic drug used as an add-on and monotherapy for a variety of seizure types in both adults and children.
Rashes due to AED including SJS and hypersensitivity syndrome leading to hospitalization occur in approximately 0.
33% of adults and 0.
8% in children.
Reactions due to LTG alone occur in around 5.
7% of cases.
We report probably the first case of this reaction in a 12-year old girl with a brief discussion on its etiology and management.
J Nepal Paediatr Soc 2012;32(2):172-174 doi: http://dx.
doi.
org/10.
3126/jnps.
v32i2.
5608.
Related Results
Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome Probably Induced by a Lamotrigine–Ginseng Drug Interaction
Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome Probably Induced by a Lamotrigine–Ginseng Drug Interaction
The likelihood of a drug reaction with lamotrigine is increased by dose escalation that is too rapid or drug interactions that increase the concentration of lamotrigine. There is a...
Isolation, characterization and semi-synthesis of natural products dimeric amide alkaloids
Isolation, characterization and semi-synthesis of natural products dimeric amide alkaloids
Isolation, characterization of natural products dimeric amide alkaloids from roots of the Piper chaba Hunter. The synthesis of these products using intermolecular [4+2] cycloaddit...
STEVEN JOHNSONS SYNDROM ON LAMOTRIGINE
STEVEN JOHNSONS SYNDROM ON LAMOTRIGINE
Introduction: Lamotrigine is an anti-epileptic drug indicated for the treatment of bipolar disorder and recurrent depressive disorders. Its efficacy has been demonstrated. However,...
First Report of Lamotrigine-Induced Drug Rash with Eosinophilia and Systemic Symptoms Syndrome with Pancreatitis
First Report of Lamotrigine-Induced Drug Rash with Eosinophilia and Systemic Symptoms Syndrome with Pancreatitis
Objective:
To report a case of lamotrigine-induced drug rash with eosinophilia and systemic symptoms (DRESS) syndrome with pancreatitis as the initial visceral ...
Lamotrigine Therapy for Bipolar Depression: Analysis of Self-Reported Patient Data (Preprint)
Lamotrigine Therapy for Bipolar Depression: Analysis of Self-Reported Patient Data (Preprint)
BACKGROUND
Depression in people with bipolar disorder is a major cause of long-term disability, possibly leading to early mortality and currently, limited s...
Lamotrigine and Stevens-Johnson Syndrome Prevention
Lamotrigine and Stevens-Johnson Syndrome Prevention
Stevens-Johnson Syndrome (SJS) is a rare life-threatening condition characterized by severe mucocutaneous epidermal necrolysis and detachment of the epidermis. The condition center...
Safety of lamotrigine in paediatrics: a systematic review
Safety of lamotrigine in paediatrics: a systematic review
Objectives
To identify adverse drug reactions associated with lamotrigine in children and compare the safety profile with other antiepileptic drugs.
...
Safety and Efficacy of Rational Polytherapy with Sodium Valproate and Lamotrigine for Pediatric Drug-Resistant Epilepsy: A Systematic Review and Meta-Analysis
Safety and Efficacy of Rational Polytherapy with Sodium Valproate and Lamotrigine for Pediatric Drug-Resistant Epilepsy: A Systematic Review and Meta-Analysis
Background: Drug-resistant epilepsy (DRE) affects approximately one-third of individuals with epilepsy, where seizures remain uncontrolled despite appropriate trials of at least tw...