A RETROSPECTIVE OBSERVATIONAL STUDY TO COMPARE THE EFFECT OF AGGRESSIVE VS MODERATE FLUID RESUSCITATION IN PATIENTS PRESENTING TO BMC SAGAR WITH ACUTE PANCREATITIS

Introduction : Acute pancreatitis is one of the most common causes of acute abdomen. Increased rates of hospitalization pose a signicant burden on health care costs and resource utilization. Our aim in this study is to assess whether moderate  Objective : uid resuscitation instead of aggressive approach would benet in the management of acute pancreatitis. :A total of 100 patients s Methods uffering from acute abdomen due to acute pancreatitis were recruited and studied in two groups. One group was managed via moderate uid resuscitation whereas the other group was managed aggressively in terms of uid therapy. The outcomes were measured as primary and secondary. Primary included the development of moderately severe or severe acute pancreatitis (according to the Revised Atlanta Classication) during the hospitalization whereas secondary compared the duration of hospital stay; intensive care unit (ICU) admission; the number of days in the ICU; the use of nutritional support and death. Results :Out of 100 subjects enrolled, 68 were males and 32females. There was no signicant between-group difference in the development of moderately severe or severe acute pancreatitis (primary outcome), which occurred in 22% of the patients in the aggressive-resuscitation group and in 19% of those in the moderate-resuscitation group. Organ failure occurred in 8% of the patients in the aggressive-resuscitation group and in 4% of those in the moderate-resuscitation group. A total of 9% of the patients in the aggressive-resuscitation group and 2% of those in the moderateresuscitation group were admitted to the ICU. Conclusion : Aggressive uid resuscitation increased the risk of volume overload. Aggressive uid resuscitation was associated with a tendency toward a higher intensity of symptoms and a longer duration of hospital stay and a higher incidence of necrotizing pancreatitis than moderate uid resuscitation.