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Supplementary Movie 7 from TRF1 Mediates Mitotic Abnormalities Induced by Aurora-A Overexpression
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Supplementary Movie 7 from TRF1 Mediates Mitotic Abnormalities Induced by Aurora-A Overexpression
American Association for Cancer Research (AACR)
Title: Supplementary Movie 7 from TRF1 Mediates Mitotic Abnormalities Induced by Aurora-A Overexpression
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Supplementary Movie 7 from TRF1 Mediates Mitotic Abnormalities Induced by Aurora-A Overexpression.
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Data from TRF1 Mediates Mitotic Abnormalities Induced by Aurora-A Overexpression
Data from TRF1 Mediates Mitotic Abnormalities Induced by Aurora-A Overexpression
<div>Abstract<p>Aurora-A, a conserved serine-threonine kinase, plays essential roles in mitosis. Aberrant upregulation of Aurora-A perturbs proper mitotic progression a...
Data from TRF1 Mediates Mitotic Abnormalities Induced by Aurora-A Overexpression
Data from TRF1 Mediates Mitotic Abnormalities Induced by Aurora-A Overexpression
<div>Abstract<p>Aurora-A, a conserved serine-threonine kinase, plays essential roles in mitosis. Aberrant upregulation of Aurora-A perturbs proper mitotic progression a...
Aurora-A Kinase: A Novel Target for the Immunotherapy Against Human Leukemias.
Aurora-A Kinase: A Novel Target for the Immunotherapy Against Human Leukemias.
Abstract
Aurora-A kinase (Aurora-A) is one of the serine/threonine kinase families, which is located on the long arm of chromosome 20q13, is mainly expressed in G2/M...
Abstract 1619: Discovering a new physiological substrate of Aurora-A kinase
Abstract 1619: Discovering a new physiological substrate of Aurora-A kinase
Abstract
Aurora-A is a serine/threonine kinase that has oncogenic properties in vivo. The expression and kinase activity of Aurora-A are up-regulated in many cancers...
Supplementary Movie 2 from TRF1 Mediates Mitotic Abnormalities Induced by Aurora-A Overexpression
Supplementary Movie 2 from TRF1 Mediates Mitotic Abnormalities Induced by Aurora-A Overexpression
Supplementary Movie 2 from TRF1 Mediates Mitotic Abnormalities Induced by Aurora-A Overexpression...
Supplementary Movie 4 from TRF1 Mediates Mitotic Abnormalities Induced by Aurora-A Overexpression
Supplementary Movie 4 from TRF1 Mediates Mitotic Abnormalities Induced by Aurora-A Overexpression
Supplementary Movie 4 from TRF1 Mediates Mitotic Abnormalities Induced by Aurora-A Overexpression...
Chromosome biorientation requires Aurora B’s spatial separation from its outer kinetochore substrates but not its turnover at kinetochores
Chromosome biorientation requires Aurora B’s spatial separation from its outer kinetochore substrates but not its turnover at kinetochores
SummaryFor correct chromosome segregation in mitosis, sister kinetochores must interact with microtubules from opposite spindle poles (biorientation). For this, aberrant kinetochor...
Abstract 2116: Therapeutic potential of T-Oligo and role of tankyrase in its mechanism of action.
Abstract 2116: Therapeutic potential of T-Oligo and role of tankyrase in its mechanism of action.
Abstract
When telomeres are disrupted, exposure of the single stranded 3’ overhang triggers DNA damage pathways resulting in cell senescence and apoptosis. T-oligo, ...