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(E)-4-Oxo-3,4-dihydroquinazoline-2-carbaldehyde Oxime
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Reaction of 4-oxo-3,4-dihydroquinazoline-2-carbaldehyde with hydroxylamine hydrochloride (1.1 equiv) in the presence of K2CO3 (1 equiv) gave (E)-4-oxo-3,4-dihydroquinazoline-2-carbaldehyde oxime (8) in 58% yield. The compound was fully characterized and the conformation of the oxime was supported by single crystal x-ray diffractometry.
Title: (E)-4-Oxo-3,4-dihydroquinazoline-2-carbaldehyde Oxime
Description:
Reaction of 4-oxo-3,4-dihydroquinazoline-2-carbaldehyde with hydroxylamine hydrochloride (1.
1 equiv) in the presence of K2CO3 (1 equiv) gave (E)-4-oxo-3,4-dihydroquinazoline-2-carbaldehyde oxime (8) in 58% yield.
The compound was fully characterized and the conformation of the oxime was supported by single crystal x-ray diffractometry.
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