ASSESSMENT OF CONGENITAL MALFORMATIONS IN CONSANGUINEOUS MARRIAGES AMONG THE FAMILIES OF STUDENTS OF SAIDU MEDICAL COLLEGE SAIDU SHARIF.

Consanguineous marriage is customary in many societies, which leads to an increased birth prevalence ofinfants with severe recessive disorders (congenital malformations). All these disorders play a significantrole on world economy, productivity and become a huge burden on medical fraternity. Majority of thesedisorders are preventable through proper “ Premarital consultation / counseling” of the male and femalebefore wedding for checking of “ Marital compatibility” .Objective of this observational study is to assess the prevalence of congenital malformations inconsanguineous marriages among the families' of students of Saidu Medical College.fMaterial & Methods:Duration of study was 3 months.Sample size Sampling Techniques: Stratified Randomized technique was used for selection of 100 houses/families of students of the college, with equal strata taken from first to final year MBBS classes.Result: From 504, 280(55.56%) of the children were from consanguineous marriages, while 224(44.45%)were from non consanguineous marriages. From 25 cases with congenital anomalies, 23 (8.2%) cases werefrom consanguineous marriages while only 2 (0.9 %) cases were from non- consanguineous marriages. Ourstudy shows that there is a significant correlation between parental marriages and the prevalence ofanomaly. 54 % couples out of 100 families were belonged to consanguineous marriages, of which 24 %,17% and 13% marriages were belonged to 1 sl cousin, 2nd cousin and other cousins respectively. 46 % out of100 families were belonged to non-consanguineous marriages.