Predictors of Post Partum Sepsis Directly Related to Pnuemonia Among Post-Partum Women at Finote Selam General Hospital, West Gojjam Zone, Amhara, Ethiopia, 2022

Abstract Introduction: Puerperal Sepsis is an inflammatory response to the infection of the female reproductive system caused by bacterial, viral, fungal, or parasitic pathogens. It affects women during or within six weeks of childbirth. For these,identification of determinants of puerperal sepsis reduces the health and economic impact through early detection and intervention. Though studies were conducted on puerperal sepsis in Ethiopia, there is a lack of information on its determinants of puerperal sepsis directly related to pneumonia in the study area. Therefore, this study aimed to identify determinants of puerperal sepsis among post-partum women at Finote Selam General Hospital, Amhara, Ethiopia, 2022. Method: Institutional based unmatched case-control study was conducted from May 10, 2022, to July 15, 2022, on post-partum women of 220 (55 cases and 165 controls with a 1:3 case-control ratio determined by the Open Epi version 3. Cases and controls were extracted by consecutive sampling. A structured face-to-face interviewer-administered questionnaire and checklist were used. Data were entered and analyzed using EPI data version 4.4.2.1 and SPSS version 25, respectively.Variables with a p-value ≤0.25 in the bi-variable logistic analysis were entered into a multivariable logistic regression model. Hosmer and Lemeshow’s goodness-of-fit test and Multicollinearity were checked. Statistical significance was declared at P-value < 0.05 along with, 95% Confidence Interval. Result: The result of multiple logistics regression revealed that the odds of developing PS directly related with post-partum pneumonia were caesarean delivery (AOR=2.802, 95 %CI: 1.207, 6.502), hypertension (AOR=2.431, 95% CI: 1.257, 4.700), history of anemia (AOR=0.343, 95%CI: 0.145, 0.811 were determinants of post-partum pneumonia. Conclusion: majority of the determinants were obstetric related.