Short-Term Outcomes of Improving Hydrostatic Pressures on Reducing Intussusception in Children

Abstract Purpose The aim of this study is to analyze the effect of increasing enema pressure on enema outcomes. Methods We conducted a retrospective study to compare the effect of increasing enema pressure on enema outcomes. The primary outcome was the success rate of reduction, while secondary outcomes included intestinal perforation and recurrence rate. Results From May 2017 to April 2021, a total of 531 intussusceptions in 499 patients (Group A 247 patients, Group B 252 patients) were collected. The overall success reduction rate was 97.00%. The success reduction rate in Group A was 99.20% (245/247) and 94.8% (239/252) in Group B (P = 0.004). The overall recurrence rate within 48 hours after the initial enema reduction was 8.02%, and beyond 48 hours was 6.41%. The recurrence rates within 48 hours and beyond 48 hours were 9.39% and 6.53% in group A and 7.11% and 6.69% in group B, respectively (P = 0.526). No complications were associated with the enema reduction procedure. Conclusion Our study has shown that using a hydrostatic pressure of 130 mmHg for enema reduction is both effective and safe, with a higher success rate and no increased risk of complications. Study type: Retrospective cohort study Level of evidence: Therapeutic study, III