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Frauke Melchior: How SUMO wrestles other proteins
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Melchior's laboratory is exploring the regulation and consequences of protein modification by the small protein SUMO.
Title: Frauke Melchior: How SUMO wrestles other proteins
Description:
Melchior's laboratory is exploring the regulation and consequences of protein modification by the small protein SUMO.
Related Results
Therapeutic Potential of Targeting the SUMO Pathway in Cancer
Therapeutic Potential of Targeting the SUMO Pathway in Cancer
SUMOylation is a dynamic and reversible post-translational modification, characterized more than 20 years ago, that regulates protein function at multiple levels. Key oncoproteins ...
SUMO: getting it on
SUMO: getting it on
Post-translational modification of cellular proteins by the SUMO (small ubiquitin-related modifier) is involved in numerous modes of regulation in widely different biological proce...
TRIM28 is a target for paramyxovirus V proteins
TRIM28 is a target for paramyxovirus V proteins
AbstractSUMO-modified Tripartite Motif Protein 28 (TRIM28; KAP1) plays a crucial role in repressing endogenous retroelement (ERE) transcription. We previously provided evidence tha...
Regulation of Ebola virus VP40 matrix protein by SUMO
Regulation of Ebola virus VP40 matrix protein by SUMO
AbstractThe matrix protein of Ebola virus (EBOV) VP40 regulates viral budding, nucleocapsid recruitment, virus structure and stability, viral genome replication and transcription, ...
Identification of heparin‐binding proteins in bovine seminal plasma
Identification of heparin‐binding proteins in bovine seminal plasma
AbstractA group of four similar proteins, BSP‐A1, BSP‐A2, BSP‐A3, and BSP‐30‐kDa, represent the major acidic proteins found in bovine seminal plasma (BSP). These proteins are secre...
Deciphering the immunogenic potential of wheat flour: a reference map of the salt-soluble proteome from the U.S. wheat Butte 86
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Abstract
Background
Within the complex wheat flour proteome, the gluten proteins have attracted most of the attention because of their importance in determining the functional prop...
Aspergillus SUMOylation mutants have normal dynein function but exhibit chromatin bridges
Aspergillus SUMOylation mutants have normal dynein function but exhibit chromatin bridges
AbstractFunctions of protein SUMOylation remain incompletely understood in different cell types. The budding yeast SUMOylation machinery interacts with LIS1, a protein critical for...
The conjugation of SUMO to the transcription factor MYC2 functions in blue light-mediated seedling development in Arabidopsis
The conjugation of SUMO to the transcription factor MYC2 functions in blue light-mediated seedling development in Arabidopsis
Abstract
A key function of photoreceptor signaling is the coordinated regulation of a large number of genes to optimize plant growth and development. The basic helix...

