Streptokinase Induce Hematuria: A Rare Compilcation Of Thrombolytic Therapy

Streptokinase is indicated for treatment of coronary artery disease. In some cases it may cause cutaneous adverse reactions. In this case hematuria was developed due to streptokinase. A 72 year old female patient had complains of breathlessness, vomiting, altered sensorium since 2 days, decrease in urine output since one day. She had known case of status post mitral valve repair in 2016 for that she was taking T. Acitron (2mg) 0-0-1,T.verapramil (20mg) 1-0-0, T.digitoxin (0.25mg) 1-0-0,T. Ecosprin (75mg) 0-1-0. One day ago patient was admitted to local hospital where she was diagnosed with acute decompensated heart failure with stuck mitral valve and patient had ventricular tachycardia eposide for that direct current shock was given and streptokinase was given due to clot on mitral valve. Patient was referred to teretery hospital within 24 hrs. Patient had hematuria due to a streptokinase and the drug was stopped and patients condition was improved. Hematuria was occurred due to streptokinase and showed some improvement