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Telogen Effluvium due to Recombinant Interferon α-2b

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Five of 10 patients receiving long-term recombinant interferon α-2b therapy complained of considerable hair loss. The pull test and the trichogram showed a telogen count consistent with a telogen effluvium. In 2 patients the telogen count progressively improved despite continuing the treatment, whereas in 3 patients the trichogram continued to show an increased telogen count until interferon therapy was discontinued. Pohl-Pinkus hair constrictions were also present in 2 patients.
Title: Telogen Effluvium due to Recombinant Interferon α-2b
Description:
Five of 10 patients receiving long-term recombinant interferon α-2b therapy complained of considerable hair loss.
The pull test and the trichogram showed a telogen count consistent with a telogen effluvium.
In 2 patients the telogen count progressively improved despite continuing the treatment, whereas in 3 patients the trichogram continued to show an increased telogen count until interferon therapy was discontinued.
Pohl-Pinkus hair constrictions were also present in 2 patients.

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