A CASE OF SYSTEMIC SCLEROSIS SINE SCLERODERMA

Systemic sclerosis is an uncommon connective tissue disorder with multisystem involvement, heterogenous clinical manifestations and have a chronic, progressive course. Autoimmune damage, vasculopathy and extensive brosis are the key etiopathogenic factors. Patients have clinical manifestations ranging from skin thickening limited to distal extremities/face to widespread multiorgan involvement. All typical features of systemic sclerosis without skin thickening is dened as SYSTEMIC SCLEROSIS SINE SCLREODERMA Case presentation: We report a case of A 40 year old female patient presented to us with the chief complaints of ulcers at the tip of right index and middle ngers associated with pain and swelling over a period of 10 days.Past history of amputation of left distal phalanx 1year back for similar complaint. She had a history suggestive of Reynaud's phenomenon. She was diagnosed as hypothyroid 5 years back with irregular treatment and with GERD 2ys back. CT CHEST-bilateral ground glass opacities,Paratracheal lymphadenopathy,Mild thyromegaly ,Mild dilatation of oesophagus,COLOUR DOPPLER-Right upper limb -normal study ,ANA PROFILE -Anti scl -70 –positive ,Anti jo 1- borderline positive Systemic sclerosis sine scleroderma (ssSSc) is an CONCLUSION : infrequent SSc variant characterized by visceral and immunological manifestations of SSc in the absence of clinically detectable skin involvement with good prognosis compared to other variants