Dexamethasone-Induced Bradycardia and Generalized Weakness in Patient with Flu Disease

The case report presented in this article describes a 36-year-old male who experienced bradycardia and generalized weakness after receiving an intramuscular injection of dexamethasone for flu treatment. This adverse effect of the medication is a rare but potentially serious occurrence that highlights the need for close monitoring of patients, particularly those with pre-existing cardiac conditions or electrolyte imbalances, following dexamethasone administration. It is essential to promptly recognize and manage symptoms of bradycardia to ensure a favorable outcome for the patient. The mechanisms underlying dexamethasone-induced bradycardia are not fully understood, but may involve potassium channel modulation and other factors. Additionally, various factors such as rapid intravenous infusion rates, underlying cardiac or renal conditions, and electrolyte imbalances can predispose individuals to corticosteroid-induced bradycardia. Thorough evaluations are necessary to rule out other potential causes of bradycardia before attributing it to corticosteroids. While most instances of corticosteroid-induced bradycardia resolve on their own, it is crucial to exclude common etiologies of sinus bradycardia and rectify any electrolyte imbalances before initiating treatment. This case report sheds light on the importance of recognizing and managing dexamethasone-induced bradycardia and highlights the need for further research into the mechanisms and risk factors associated with this adverse effect.