Dedifferentiated liposarcoma of the spermatic cord: A case report

Introduction: Soft tissue sarcomas account for and #60;1% of all adult malignancies with the most commonly reported being liposarcomas, leiomyosarcomas, or rhabdomyosarcomas. Genitourinary tract (GU) sarcomas are considered as an even more rare subtype of soft tissue sarcomas. A patient who presented with a unilateral painless mass initially diagnosed as a high-grade undifferentiated spindle cell neoplasm most consistent with sarcoma by intralesional excisional biopsy found to be a primary undifferentiated spindle cell sarcoma arising from the left-sided spermatic cord. Final diagnosis after radical resection of the mass was dedifferentiated liposarcoma most likely arising from the spermatic cord. After resection of the mass, the patient was diagnosed with a dedifferentiated liposarcoma most likely arising from the spermatic cord. There is sparse literature on this type of spermatic cord sarcoma. The goal of this case report is to summarize the findings that led to this rare diagnosis. Case Report: This is the case of an 81-year-old white male who presented to his primary care physician due to a mass in his left groin. After initial clinical misdiagnosis and mismanagement, the patient underwent incisional biopsy and was diagnosed with a stage IIIB, cT3 N0 M0 primary undifferentiated spindle cell sarcoma of the left-sided spermatic cord, grade 3. Upon radical resection, the final diagnosis was high grade dedifferentiated liposarcoma measuring 8.8 × 5.0 × 4.8 cm. Conclusion: There is currently a paucity of literature on dedifferentiated liposarcomas arising from the spermatic cord. The patient was initially diagnosed with an undifferentiated spindle cell sarcoma thought to have arisen from the spermatic cord, however, upon undergoing radical resection, the final diagnosis was determined to be a high grade dedifferentiated liposarcoma. This case discusses the rare diagnosis of a dedifferentiated liposarcoma most likely arising from the spermatic cord. It is believed that clinicians should consider malignancy in the differential diagnosis of patients presenting with an inguinal mass.