Abstract Fri057: Outcomes in Breast Cancer Patients with STEMI and NSTEMI: A Multiyear Comparison of Cardiovascular Events and Interventions

Breast cancer is a major health concern with significant morbidity and mortality, especially in patients with cardiovascular events. Understanding its interaction with cardiovascular outcomes is essential for improving care. This study evaluates the association between breast cancer and cardiovascular outcomes, including mortality, cardiogenic shock, acute kidney injury, vasopressor use, transfusion needs, and other events in STEMI and NSTEMI patients. This study examines how breast cancer affects cardiovascular outcomes in STEMI and NSTEMI, assessing differences in mortality, cardiogenic shock, acute kidney injury, vasopressor use, transfusion needs, gastrointestinal bleeding, sepsis, cerebrovascular accident, intubation, cardiac arrest, and PCI and CABG rates. The goal is to determine potential protective or adverse effects. The objective is to evaluate the impact of breast cancer on cardiovascular events and interventions in STEMI and NSTEMI patients. Using a national inpatient dataset, this study quantifies outcome disparities, evaluates healthcare access, and informs cardiovascular care strategies for breast cancer patients. A multiyear retrospective analysis of the National Inpatient Sample (2017–2022) was conducted. Logistic regression models examined associations between breast cancer and cardiovascular outcomes. Patients were stratified by STEMI and NSTEMI, adjusting for demographics, socioeconomic status, hospital region, and comorbidities. Outcomes included mortality, cardiogenic shock, acute kidney injury, vasopressor use, transfusions, gastrointestinal bleeding, sepsis, cerebrovascular accident, intubation, cardiac arrest, PCI, and CABG. In STEMI patients, breast cancer was associated with lower mortality, cardiogenic shock, acute kidney injury, vasopressor use, transfusion, gastrointestinal bleeding, sepsis, cerebrovascular accident, intubation, and higher PCI use. In NSTEMI patients, breast cancer was linked to lower mortality, acute kidney injury, vasopressor use, transfusion, gastrointestinal bleeding, sepsis, cerebrovascular accident, intubation, and higher PCI use. Breast cancer patients with STEMI and NSTEMI had fewer adverse cardiovascular outcomes and were more likely to receive PCI, likely due to increased healthcare interactions. Enhanced surveillance and access to care may explain these better outcomes. Further research should explore healthcare access and treatment factors influencing cardiovascular health in this population.