Clinical Application of One-Position Complete Retroperitoneoscopic Nephroureterectomy

Abstract Objective: To explore the surgical method and the clinical efficacy of complete retroperitoneal laparoscopic radical resection of upper tract urothelial carcinoma (UTUC). Methods: A retrospective analysis of 83 patients with upper urothelial carcinoma from January 2016 to December 2019 in the Affiliated Hospital of Xuzhou Medical University was conducted. Among them, 40 patients underwent one-position complete retroperitoneoscopic nephroureterectomy (CRNU) and 43 patients underwent traditional retroperitoneoscopic nephroureterectomy (TRNU). Compare the differences in clinical data, perioperative parameters and postoperative follow-up results of patients with the two surgical methods. CTU and ureteroscopy were used to diagnose. Results: A total of 43 patients (35 males and 8 females) with TRNU were enrolled in this study. Forty patients (31 males and 9 females) received CRNU. The CRNU group had significantly shorter average operation time (105.83±5.80 min versus 147.28 ± 17.58 min) and lower visual pain score (P=0,024). No significant difference was found in age, BMI, T stage, complication, change of albumin and hemoglobin, postoperative hospital stays and tumor recurrence (P>0.05). Conclusion: one-position complete retroperitoneoscopic nephroureterectomy is safe and feasible. The curative effect is affirmative. It has the conspicuous advantages in minimally invasive, no posture change, less postoperative pain, less interference with abdominal organ and shorter operation time, which could particularly reduce the workload of operating room nurses without any additional postoperative complications.