Tremors

Abstract Descriptions of tremor encompass ancient civilizations to the present day. This book covers the increasingly rich and diverse research arena in tremors, and how research connects with improved recognition and treatment of tremors. The initial book sections cover fundamental concepts in tremor nosology and classification, pathophysiology, and etiology. “Tremor Foundations,” presents work across research modalities, providing an overview on the underpinnings of tremor as symptom and disease. Recent developments in the understanding of tremor pathology, pathophysiology, and genetics, spurred by new basic research and neuroimaging techniques, illustrate the breadth of immediate opportunity in tremor research. “The Family of Tremors” presents the extended range of tremors, spanning isolated tremors, tremor as one of several features of a neurological disorder or medical disease, and other hyperkinetic movement phenotypes commonly referred to, mimicking, or framed as tremors. The final section, “Tremor in the Clinic,” puts the fundamental concepts of the initial sections into clinical context. This section covers current and emerging frameworks for assessment, diagnosis, and holistic treatment of tremors, and the accelerating growth in new therapeutics development. All sections connect across key concepts in defining and working with tremors, illustrating how work in state-of-the-art clinical care feeds back into understanding causes of tremors and new therapeutics development. Tremor is one of the most common movement disorders. This dynamic, rich topic is sure to see continued rapid growth in research and clinical care options.