Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Crystallin Composition of the Bovine Lens Epithelium Related to Aging
View through CrossRef
The bovine lens epithelial cells contain two α-crystallins, one pre-α-crystallin, three β-crystallins and one γ-crystallin, as detected by immunoelectrophoresis with polyvalent and specific antisera. With aging, one of the two molecular forms of epithelial α-crystallin disappears. The β-crystallins of the epithelium may also change with aging, and the epithelial γ-crystallin differs structurally from the γ-crystallins in the equator and nucleus. Except one pre-α-crystallin, one α-crystallin and one γ-crystallin, all other crystalline which are present in the epithelium are also found in the other lens parts.
Title: Crystallin Composition of the Bovine Lens Epithelium Related to Aging
Description:
The bovine lens epithelial cells contain two α-crystallins, one pre-α-crystallin, three β-crystallins and one γ-crystallin, as detected by immunoelectrophoresis with polyvalent and specific antisera.
With aging, one of the two molecular forms of epithelial α-crystallin disappears.
The β-crystallins of the epithelium may also change with aging, and the epithelial γ-crystallin differs structurally from the γ-crystallins in the equator and nucleus.
Except one pre-α-crystallin, one α-crystallin and one γ-crystallin, all other crystalline which are present in the epithelium are also found in the other lens parts.
Related Results
Towards the Identification and Characterization of Putative Adult Human Lens Epithelial Stem Cells
Towards the Identification and Characterization of Putative Adult Human Lens Epithelial Stem Cells
The anterior lens epithelium has the ability to differentiate into lens fibres throughout its life. The present study aims to identify and functionally characterize the adult stem ...
MsrA repair of Cytochrome c and α‐crystallin links chaperone and oxidative repair pathways with mitochondrial protection and apoptotic control in lens cells.
MsrA repair of Cytochrome c and α‐crystallin links chaperone and oxidative repair pathways with mitochondrial protection and apoptotic control in lens cells.
Abstract Purpose Methionine sulfoxide reductase A (MsrA) is essential for lens defense against oxidative stress and cataract formation through its ability to repair oxidized protei...
αB-crystallin is involved in the process of pulmonary fibrosis
αB-crystallin is involved in the process of pulmonary fibrosis
Introduction:
Idiopathic Pulmonary Fibrosis (IPF) is a devastating disease with currently no treatment. In the presence of TGF-β, epithelial cells differentiate...
Effects of α-crystallin gene knockout on zebrafish lens development
Effects of α-crystallin gene knockout on zebrafish lens development
Abstract
The α-crystallin small heat shock proteins contribute to the transparency and refractive properties of the vertebrate eye lens and preve...
Structural perturbation and enhancement of the chaperone‐like activity of α‐crystallin by arginine hydrochloride
Structural perturbation and enhancement of the chaperone‐like activity of α‐crystallin by arginine hydrochloride
AbstractStructural perturbation of α‐crystallin is shown to enhance its molecular chaperone‐like activity in preventing aggregation of target proteins. We demonstrate that arginine...
Why does the zebrafish
cloche
mutant develop lens cataract?
Why does the zebrafish
cloche
mutant develop lens cataract?
Abstract
The zebrafish has become a valuable model for examining ocular lens development, physiology and disease. The zebrafish
...
Biophysical Insights into Implications of PEG-400
on the α-Crystallin Structure: Multispectroscopic and Microscopic
Approach
Biophysical Insights into Implications of PEG-400
on the α-Crystallin Structure: Multispectroscopic and Microscopic
Approach
Abstract
Aggregation and precipitation of α-crystallin play a vital role in the cataract development. This study was targeted to delineate the effect of PEG-400 o...
Photosensitized Effects of Rose Bengal on Structure and Function of Lens Protein “Alpha‐Crystallin”
Photosensitized Effects of Rose Bengal on Structure and Function of Lens Protein “Alpha‐Crystallin”
AbstractThe conformational changes of the bovine lens protein “α‐crystallin” have been investigated in the presence of the photosensitizer Rose Bengal (RB), in the dark as well as ...