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Thiazine-2-thiones as Masked 1-Azadienes in Cascade Dimerization Reactions)
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We report the unexpected formation of a 1-azadiene dimer from 4,6-diphenyl-3,6-dihydro-2H-1,3-thiazine-2-thiones under prolonged microwave irradiation. In this manner, thiazine-2-thiones act as “masked” 1-azadiene equivalents, which makes them useful synthetic tools to access complex heterocyclic frameworks. We compare this dimerization with earlier approaches and elaborate on the observed diastereoselectivity.
Title: Thiazine-2-thiones as Masked 1-Azadienes in Cascade Dimerization Reactions)
Description:
We report the unexpected formation of a 1-azadiene dimer from 4,6-diphenyl-3,6-dihydro-2H-1,3-thiazine-2-thiones under prolonged microwave irradiation.
In this manner, thiazine-2-thiones act as “masked” 1-azadiene equivalents, which makes them useful synthetic tools to access complex heterocyclic frameworks.
We compare this dimerization with earlier approaches and elaborate on the observed diastereoselectivity.
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