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Radioprotective Mechanisms of Arbutin: A Systematic Review
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Purpose:
Efforts to produce radioprotective agents of high potential are appropriate
strategies for overcoming possible IR toxicity in organisms. The present research aims to evaluate
the signaling pathways and mechanisms through which arbutin exerts radioprotective effects on
organisms.
Methods:
The databases of PubMed, Web of Sciences, Google Scholar, and Scopus were searched
to find studies that reported radioprotective effects for arbutin. Besides, the data were searched
within the time period from 2010 to 2020.
Result:
Five research articles met our criteria, which were included in the analysis based on their
relevance to the topic. The present systematic review provides conclusions about various mechanisms
and pathways through which arbutin induces radioprotection.
Conclusions:
Based on the relevant studies, various mechanisms can be proposed for inducing
radioprotective effects by arbutin, including inhibition of oxidative stress, apoptosis, and inflammation.
Bentham Science Publishers Ltd.
Title: Radioprotective Mechanisms of Arbutin: A Systematic Review
Description:
Purpose:
Efforts to produce radioprotective agents of high potential are appropriate
strategies for overcoming possible IR toxicity in organisms.
The present research aims to evaluate
the signaling pathways and mechanisms through which arbutin exerts radioprotective effects on
organisms.
Methods:
The databases of PubMed, Web of Sciences, Google Scholar, and Scopus were searched
to find studies that reported radioprotective effects for arbutin.
Besides, the data were searched
within the time period from 2010 to 2020.
Result:
Five research articles met our criteria, which were included in the analysis based on their
relevance to the topic.
The present systematic review provides conclusions about various mechanisms
and pathways through which arbutin induces radioprotection.
Conclusions:
Based on the relevant studies, various mechanisms can be proposed for inducing
radioprotective effects by arbutin, including inhibition of oxidative stress, apoptosis, and inflammation.
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